Keynote Speaker
– Madalena M. M. Pinto, “XANTHONE: an old “dog” that learns new tricks…“, The Sixth International Symposium on Pharmaceutical and Biomedical Sciences, May 26-28, 2022, Gaziantep University, Turkey (online).
Plenaries
– Madalena M. M. Pinto, “MEDICALIZAÇÃO versus DESMEDICALIZAÇÃO: Quo vadis?” Conferência de abertura da 4ª Edição da Escola de Inverno de Farmácia, Porto, Portugal, Março 18-27, 2019.
– Madalena M. M. Pinto, “Medicalização do “humor” e do “amor”…sim ou não ?”, Lição inaugural, CERIMÓNIA SOLENE DE ABERTURA do Novo Ano Letivo CESPU, Instituto Universitário das Ciências da Saúde, Gandra, 25 november 2017
– Madalena M. M. Pinto, “Nature-mimetic small molecules: From the land, from the sea, from the lab and through the looking-glas…”, 8th Brazilian Symposium on Medicinal Chemistry, Búzios, Rio de Janeiro, Brazil, November 27- 30, 2016
– Madalena M. M. Pinto, Chiral derivatives of xanthones: bioactive small molecules and analytic tools, 3rd Portuguese Meeting on Medicinal Chemistry, 1st Portuguese- Spanish-Brazilian Meeting on Medicinal Chemistry,28-30 November 2012
– Madalena M. M. Pinto, Ciclo de conferências “A investigação nas ciências farmacêuticas” Ciências Farmacêuticas: ontem, hoje e amanhã, no âmbito das comemorações do Centenário de Aníbal Cunha, Salão nobre complexo ICBAS-FFUP, 27 september de 2012
– Madalena M. M. Pinto, A Química Medicinal e o Ambiente: a (inter)ligação “perfeita ?, 3rd Portuguese Meeting on Medicinal Chemistry, 1st Portuguese- Spanish-Brazilian Meeting on Medicinal Chemistry,28-30 November 2012
– Madalena M. M. Pinto, “At the Cross Roads of Chemistry, Biology, and Nanothecnology”, 3rd Congress of the Portuguese Society of Pharmaceutical Sciences, 9th Portuguese-Spanish Conference on Controlled Drug Delivery, Porto, Portugal, 13-15 October 2011
– Madalena M. M. Pinto “Pequenas moléculas multiativas: estruturas “promíscuas” ou “privilegiadas”, eis a questão!”, no âmbito do CONHECIMENTO NA UP, Porto, 26 Maio 2011
Invited Speaker
– Madalena M. M. Pinto*, Maria Elizabeth Tiritan, Carla Fernandes, “Chiral xanthone derivatives: synthesis, biological activities and analytical applications”, The 5th International Mediterranean Symposium on Medicinal and Aromatic Plants (MESMAP – 5) and 5th International Symposium on Pharmaceutical and Biomedical Sciences (ISPBS-5), Cappadocia, Turkey, April 24-26, 2019.
-Madalena M. M. Pinto, “Resveratrol: a molecule with chameleonic properties – Chemical strategies for topical application” The 4th International Mediterranean Symposium on Medicinal and Aromatic Plants (MESMAP – 4), Antalya, Turkish Republic of Northern Cyprus April 18-22, 2018.
– Madalena M. M. Pinto, “From the land and the sea: a library of xanthone natural mimics looking for biological diversity”, The Third International Mediterranean Symposium on Medicinal and Aromatic Plants (MESMAP – 3), Girne-Turkish Republic of Northern Cyprus April 13th – 16th, 2017.
– Madalena M. M. Pinto, “Xanthone derivatives: a chemical library of natural mimics for biological diversity”. 6th International Conference on Natural Products for Health and Beuty (NATPRO-6), Khon Kaen, Thailand, 21-23 January, 2016
– Madalena M. M. Pinto, “Chiral derivatives of xanthones: from bioactive small molecules to analytic tools”, Faculty of Sciences, Kasetsart University, Bangkok, Thailand, Portugal, 11 November 2014
– Madalena M. M. Pinto, “Dual anticoagulant/antiplatelet small molecules: overcoming the limitations of antithrombotic therapy”, Faculty of Sciences, Kasetsart University, Bangkok, Thailand, Portugal, 11 November 2014
– Madalena M. M. Pinto, “Multifunctional novel small-molecules to overcome drug resistance in cancer”, no XX Porto Cancer Meeting, Porto, Portugal, 28-29 April, 2011
– Madalena M. M. Pinto, “Xanthone Derivatives: ‘Promiscuous’ or ‘Priviledge’, that’s the question!”, 5th Brazilian Symposium on Medicinal Chemistry (BRAZMEDCHEM), Ouro Preto-MG, Brazil, 6-9 November, 2010
– Madalena M. M. Pinto, “Caminhos Cruzados da Química e Biologia”, in “Conferência: Microbiologia e Biologia do Cancro”, Faculty of Pharmacy, University of Porto, Portugal, 11 de Dcember 2009.
– Madalena M. M. Pinto, “At the crossroads of Chemistry and Biology: hits and leads generation”, Faculty of Science, Kasetsart University, Bangkok, Thailand (28 November 2008).
– Madalena M. M. Pinto, “Classic and Rational Strategies for Bioactive Xanthones”, Department of Pharmacology, Faculty of Medicine, University of Khon Kaen, Khon kaen, Thailand, 17 Janeiro de 2005.
– Madalena M. M. Pinto, “Xantone derivatives in the context of the search for new drugs “- Pos-graduate Course in Science, Education and Inovation, University of Porto (21 October 2003)
– Madalena M. M. Pinto, “The influence of the Organic Chemistry in Medicinal Chemistry”- 23ª Reunião Anual da Sociedade Brasileira de Química “Brasil 500- A Ligação Química Brasil/Portugal”, Poços de Caldas. Minas Gerais, Brasil (23 – 26 May 2000)
– Madalena M. M. Pinto, “Medicinal Chemistry – A via to new drugs” – III Jornadas Internacionais da COFANOR, Fundação Eng. António de Almeida, Porto (21 October 1999)
– Madalena M. M. Pinto, “Heterocycles: Their importance in Medicinal Chemistry” – Department of Chemistry, University of Minho (18 June 1999)
– Madalena M. M. Pinto, “Xanthones and Xanthonolignoids – Synthesis and Biological Activity” – Faculty of Pharmacy, University of Lausanne, Switzerland (11 July 1995)
– Madalena M. M. Pinto, “Non classic Pharmacochemistry: What future? Faculdade de Farmácia da Universidade de Lisboa (24 June 1992).
– Madalena M. M. Pinto, “Supramolecular Chemistry applied to Medicinal Chemistry” Chemistry Department of Nova University of Lisbon, Portugal (4 de Maio de 1992).
– Madalena M. M. Pinto, “Nature: Model for Chemists”- Portuguese Society of Biology, Faculty of Sciences, Porto, Portugal Porto (14 de December de 1984).
Invited Oral Communications
– E. Silva, C. Vilas Boas, A. R. Neves, F. Carvalhal, A. Campos, V. Vasconcelos, M. Pinto, E. Sousa, J. R. Almeida, M. Correia-da-Silva. Helping marine industry to face the phase-out of current highly hazardous biocides: new nature-inspired antifouling compounds obtained by synthesis. 13th National Organic Chemistry Meeting – 6th National Medicinal Chemistry Meeting, 13ENQO-6ENQT, Aveiro, Portugal, 15 -17 January 2020.
– S. Long, D. I. S. P. Resende, P. Pereira-Terra, J. Freitas-Silva, A. M. S. Silva, M. E. Tiritan, A. Kijjoa, E. Pinto, P. Costa, M. Pinto, E. Sousa, Synthetic strategies towards bioactive nature-inspired indole-containing alkaloids, (doi:10.3390/ECMC2019-06291), 5th International Electronic Conference on Medicinal Chemistry, November 1-30, 2019.
– E. Sousa, S. Gomes, L. Raimundo, J. Soares, J. B. Loureiro, M. Leão, H. Ramos, M. N. Monteiro, Agostinho Lemos, Joana Moreira, Madalena Pinto, Petr Chlapek, Renata Veselska, Lucília Saraiva. Strategies to discover p53 activators and a p73 activator for neuroblastoma. 2nd Molecules Medicinal Chemistry Symposium – Facing Novel Challenges in Drug Discovery, Barcelona, Spain, 15- 17 May 2019.
– Emília Sousa, Sara Gomes, Liliana Raimundo, Joana Soares, Joana B. Loureiro, Mariana Leão, Helena Ramos, Madalena N. Monteiro, Agostinho Lemos, Joana Moreira, Madalena Pinto, Petr Chlapek, Renata Veselska, Lucília Saraiva. “Strategies to discover p53 activators and a p73 activator for neuroblastoma”. 2nd Molecules Medicinal Chemistry Symposium – Facing Novel Challenges in Drug Discovery, Barcelona, Spain, 15-17 May 2019
– Emília Sousa, Ana Oliveira, Marta Correia-da-Silva, Vanessa Rodrigues, Raquel T. Lima, M. Helena Vasconcelos, Madalena Pinto, “Curcumin, a valuable model for new cytotoxic agents to circumvent multidrug resistance”, 6th International Conference on Natural Products for Health and Beuty (NATPRO-6), Khon Kaen, Thailand, 21-23 January, 2016
– M. Correia-da-Silva, J. R. Almeida, Isabel Cunha, E. Sousa, M. Pinto, V. Vasconcelos. “Other face of the anticoagulant sulfated molecules coin: the promising of non-toxic antifouling agents”. First International Christmas Caparica Congress in Translational Chemistry IC3TC-2015, Lisbon, Portugal, December 7-10, 2015
– Sousa, E.; Palmeira, A.; Oliveira, A.; Lopes-Rodrigues, V.; Correia-da-Silva, M.; Lima, R. T.; Vasconcelos, M. H.; Pinto, M. M., “Thioxanthones derivatives as dual inhibitors of P-glycoprotein and tumor cell growth”., W11-4. 51st Congress of the European Societies of Toxicology – EUROTOX 2015, Porto, Portugal, September-13-16, 2015.
– M. Teixeira, M. Pedro, F. Cerqueira, M. S. J. Nascimento, M. M. M. Pinto and C. M. Barbosa, “Contribution of Nanotechnology to Optimize the Delivery of Xanthone Derivatives”, 1st National Meeting on Medicinal Chemistry, Faculty of Sport Science of the University of Porto, Portugal, 13 – 15 November 2008
– A. F. Palmeira1, A. Paiva, E. Sousa, M. Pinto, H. Seca , G. M. Almeida, R. T. Lima, M. H. Vasconcelos, “XP13 – A Novel Xanthone Derivative with Antiproliferative and Apoptotic Effects in Leukaemia Cell Lines”, 1st National Meeting on Medicinal Chemistry, Faculty of Sport Science of the University of Porto, Portugal, 13 – 15 November 2008
– César Portela, Carlos M. M. Afonso, Madalena M. M. Pinto, Maria João Ramos, “New xanthonic ligands with potential antimalarial activity: Rational design and synthesis”, 6º Encontro Nacional de Química Orgânica, Universidade do Minho, Braga, 20 -22 de July 2005.
– Madalena. M.M. Pinto, “Xanthone Derivatives: an Iberoamerican Chemical Bridge?” Reunião de Coordenação do Subprograma X, Química Fina Farmacêutica, Workshop: “Novas aproximações para descoberta de fármacos. Possibilidades e limitações na América Latina”, Rio de Janeiro (Brasil), 19-24 August 2001.
– M.M.M. Pinto, M.E. Sousa, C. Afonso, A. Silva, O. R. Gottlieb, M. S. J. Nascimento, M. Pedro, F. Cerqueira, “Natural Kielcorins as a Model for Design and Synthesis of Novel Bioactive Compounds”, IUPAC 22th International Symposium on the Chemistry of Natural Products, São Carlos, Brazil, 4-8 September, 2000.
– Madalena M. M. Pinto, “The Colors of the Health in the Plant Kingdom”, XVI Encontro Nacional da Sociedade Portuguesa de Química, Guimarães, 22 – 25 de September, 1998.
– Madalena M. M. Pinto, “Molecular Clefts in Molecular Recognition of Antiviral Agents”, XV Encontro Nacional da Sociedade Portuguesa de Química, Porto, 22 – 25 May, 1996.
– Madalena M. M. Pinto, “Bioactivity of Xanthones and Derivatives – The involvement of Free Radials” – 2º Congresso de Radicais Livres em Química, Biologia e Medicina, Faculdade de Ciências do Porto, 23 -25 de October, 1995.
– Madalena M. M. Pinto, “Natural Products: Molecular Diversity versus Bioactivity ” 14º Encontro Anual da Sociedade Portuguesa de Química, Universidade de Aveiro, 5 a 8 de April, 1994.
– Madalena M. M. Pinto, “Supramolecular Chemistry applied to Pharmacochemistry” ” 13º Encontro Anual da Sociedade Portuguesa de Química, Instituto Superior Técnico, 29 January a 1 February, 1992.
Oral Communications (last 5 years)
– Oral Communications in National Conferences:
– R. Cristelo, C. Carvalho, B. Duarte, F. Marques, S. G. Monteiro, M. Morato, M. Pinto, E. Sousa, M. C. Silva. New synthetic coumarin derivative as a heparin mimetic. IJUP’20, Encontro de Investigação Jovem da Universidade do Porto, 13ª Edição, Reitoria da Universidade do Porto, 12 -14 February 2020.
– Gonçalves; C.; Neves, A. R.; Pereira, D.; Sousa, E.; Pinto, M.; Vasconcelos V.; Cidade, H.; Almeida, J.; Correia da Silva, M. In vivo, in vitro and in silico studies of new antifouling compounds obtained by synthesis. IJUP’20, Encontro de Investigação Jovem da Universidade do Porto, 13ª Edição, Reitoria da Universidade do Porto12 -14 February 2020
– M. C. Almeida, D. I. S. P. Resende, B. Maciel, H. Carmo, I. F. Almeida, J. M. Sousa Lobo, C. Pozzo, S. Cravo, G. P. Rosa, A. Kane-Pagès, M. Carmo Barreto, M. Pinto, E. Sousa. Polyoxygenated xanthones with skin anti-aging potential. IJUP’20, Encontro de Investigação Jovem da Universidade do Porto, 13ª Edição, Reitoria da Universidade do Porto, 12 -14 February 2020
– G. Sousa, C. Vilas-Boas, M. Pinto, E. Sousa, M. Correia-da-Silva. Environmental impact of new antifouling xanthones. Simpósio de Investigação da Faculdade de Farmácia da Universidade do Porto (SIFFUP), Associação de Estudantes da Faculdade de Farmácia da Universidade do Porto (AEFFUP), 26 November 2019.
– M. C. Almeida, D. I. S. P. Resende, M. Pinto, I. F. Almeida, E. Sousa. Towards the synthesis of a polyoxygenated xanthone with skin anti-aging potential. Simpósio de Investigação da Faculdade de Farmácia da Universidade do Porto (SIFFUP), Associação de Estudantes da Faculdade de Farmácia da Universidade do Porto (AEFFUP), 26 November 2019
– R. Cristelo, C. Carvalho, B. Duarte, F. Marques, S. G. Monteiro, M. Morato, M. Pinto, E. Sousa, M. Correia da Silva. Hybrids of sulfated glycosides and coumarins as new anticoagulant agents. Simpósio de Investigação da Faculdade de Farmácia da Universidade do Porto (SIFFUP), Associação de Estudantes da Faculdade de Farmácia da Universidade do Porto (AEFFUP), 26 November 2019.
– F. Barbosa, F. Durães, J. Cardoso, M. Pinto, E. Pinto, E. Sousa. Aminothioxanthonic derivatives: synthesis and study of antifungal synergistic effect. Simpósio de Investigação da Faculdade de Farmácia da Universidade do Porto (SIFFUP), Associação de Estudantes da Faculdade de Farmácia da Universidade do Porto (AEFFUP), 26 November 2019
– Long S.; Resende D.; Pereira-Terra P.; Freitas-Silva J. Silva A.; Tiritan M. E.; Kijjoa A.; Pinto E.; Costa P.; Pinto M.; Sousa E. “Synthesis and Biological Evaluation of Nature-Inspired Indole-Containing Alkaloids”, XXVI Encontro Nacional da SPQ, Faculdade de Ciências, Universidade do Porto, Porto, Portugal, 24-26 July 2019
– E. Martins, D. J. Barbosa, E. Sousa, D. Resende, M. Pinto, F. Remião, R. Silva. In Vitro Modulation of P-Glycoprotein by Xanthonic Derivates: Implications on Alzheimer’s Disease. XLIX Reunião da Sociedade Portuguesa de Farmacologia, XXXVII Reunião de Farmacologia Clínica e XVIII Reunião de Toxicologia, Porto, Portugal, 6- 8 February 2019.
– M. N. Monteiro, S. Gomes, L. Raimundo, J. Soares, J. B. Loureiro, M. Leão, H. Ramos, M. Pinto, P. Chlapek, R. Veselska, E. Sousa, L. Saraiva. Improving neuroblastoma therapy with a new tap73 activator. XLIX Reunião da Sociedade Portuguesa de Farmacologia, XXXVII Reunião de Farmacologia Clínica e XVIII Reunião de Toxicologia, Porto, Portugal, 6- 8 February 2019.
– Ana Rita Franco, Daniela Pereira, Marta Correia da Silva, Madalena Pinto, Honorina Cidade, The application of click chemistry in the synthesis of new potential antifouling chalcones, 12º Encontro de Jovens Investigadores da Universidade do Porto, Porto, Portugal, February 13-15, 2019
– Ana Maia, Daniela R. P. Loureiro, José X. Soares, Daniela Lopes, Carlos M. Azevedo, Madalena M. M. Pinto, Salette Reis, Carlos M. M. Afonso. Binding lipophilicity with passive permeation of drugs: analysis of different BCS classes. 12º Encontro de Jovens Investigadores da Universidade do Porto, Porto, Portugal, February 13-15, 2019
– Álvaro F. Magalhães, J. Soares, D. Loureiro, S. Cravo, C. Azevedo, M. Pinto, C. Afonso; Route to xanthone derivatives and in silico determination of their biophysicochemical properties. 11th Meeting of Young Researchers of University of Porto (IJUP18), Porto, Portugal, February 7-9, 2018.
– B. Martins, M. Correia da Silva, D. Pereira, J. Almeida, V. Vasconcelos, M. Pinto, H. Cidade, Synthetic analogues of marine natural flavonoids: synthesis and biological evaluation. 11th Meeting of Young Researchers of University of Porto (IJUP18), Porto, Portugal, February 7-9, 2018.
– C. Leite, C. Fernandes, M.E. Tiritan, M. Pinto, Synthesis of a xanthone derivative by a multi-step pathway via benzophenone, IJUP 2018, 11th Meeting of Young Researches of University of Porto, 7-9 February, 2018.
– J. Ribeiro, C. Fernandes, M.E. Tiritan, M.M.M. Pinto, Chiral stationary phases based on amylose and cellulose derivatives, IJUP 2018, 11th Meeting of Young Researches of University of Porto, 7-9 February, 2018.
– J.P. Carmo, C. Fernandes, M.E. Tiritan, C. Afonso, M.M.M. Pinto, Chiral recognition of xanthone derivatives on human serum albumin stationary phase: effect of chromatographic conditions, IJUP 2018, 11th Meeting of Young Researches of University of Porto, 7-9 February, 2018.
– C. Fernandes, M.E. Tiritana, M.M.M. Pinto, New brush-type chiral stationary phases based on xanthone derivatives for liquid chromatography, 10º Encontro Nacional de Cromatografia, Bragança, 4-6 December, 2017.
– Vilas-Boas, C.; Cravo, S.; Sousa, E.; Pinto, M.; Correia-da-Silva, M. Seawater degradation studies of gallic acid persulfate, a promising synthetic antifouling agent. 10º Encontro Nacional de Cromatografia (10ENC), Bragança, Portugal, December 04-06, 2017.
– I. Hrynchak, A. Reis-Mendes, M. L. Bastos, M. Pinto, V. M. Costa, E. Sousa, “Old Sources for New Drugs: Challenges and Opportunities”, SPQ National Meeting (XXVEN-SPQ), Lisbon, Portugal, 16-19 July 2017, KN1.
– A. Reis-Mendes, S. Gomes, R. Carvalho, F. Carvalho, F. Remião, M. Pinto, M. L. Bastos, E. Sousa, V. M. Costa. Mitoxantrone and its naphthoquinoxaline metabolite: a comparative study in differentiated h9c2 cells. XLVII Reunião Anual da Sociedade Portuguesa de Farmacologia XXVI Reunião De Farmacologia Clínica XVII Reunião De Toxicologia, Coimbra, Portugal, 2- 4 de February 2017, C122.
– B. Freitas, C. Fernandes, M.E. Tiritan, A.M.S. Silva, M.M.M. Pinto, Strategy for synthesis of chiral derivatives of xanthones in enantiomerically pure form, IJUP 2017, 10th Meeting of Young Researches of University of Porto, 8-10 February, 2017.
– A. Lopes, E. Martins, R. Silva, C. Fernandes, A. Palmeira, F. Remião, M.M.M. Pinto, E. Sousa, Small Chiral Molecules as potential P-gp Modulators: Synthesis and Studies of Enantioselectivity, IJUP 2017, 10th Meeting of Young Researches of University of Porto, 8-10 February, 2017.
– P. Pinto, P.M.A. Silva, S. Marques, J. Costa, J. Moreira, A. Palmeira, M. Pinto, J. Salvador, H. Bousbaa, H. Cidade, “Synthesis of Bioactive Chalcones and Their Heterocyclic Derivatives as Potential Antitumor Agents” IJUP 2017 -10th Meeting of Young Researches of U. Porto, Porto, Portugal, 8-10 February, 2017.
– M.I.S. Cruz, S.M. Cravo, H. Cidade, M. Pinto, “Synthesis and Biological Evaluation of Xanthone and Flavone Derivatives as Potential Dual Agenst to Combat Alzheimer’s Diasease”, IJUP 2016 -9th Meeting of Young Researches of U. Porto, Porto, Portugal, 17-19 February, 2016 (10896).
– J. Moreira, S. Salazar, M. Pinto, M. Leão, M. Pinto, L. Saraiva, H. Cidade, “Flavonoid derivatives with caspase modulatory activity” IJUP 2016 – 9th Meeting of Young Researches of U. Porto, Portugal, 17-19 February, 2016 (10868).
– Raimundo, L.; Gomes, S.; Leão, M.; Soares, J.; Ramos, H.; Bessa, C.; Pinto, M.; Inga, A.; Cidade, H.; Saraiva, L. Enhanced cytotoxicity against human tumor cells using prenylated chalcones through disruption of the p53-MDM2 interaction. XXII Encontro Luso-Galego de Química, November 9-11, 2016 (O58, pag. 216).
– Oral Communications in International Conferences:
– Neves, A. R.; Almeida, J. R.; Antunes, J.; Vasconcelos, V.; Pinto, M.; Sousa, E.; Elisabete R. Silva, Correia-da-Silva, M. Polymeric coatings containing new antifouling synthetic bile acid derivatives to prevent marine biofouling. AMB14 XXV Encontro Galego-Portugués de Química, Santiago de Compostela, Espanha, 20 – 22 de November 2019.
– S. Long, D. I. S. P. Resende, A. Kijjoa, A. M. S. Silva, R. Fernandes, C. P. R. Xavier, M. H- Vasconcelos, E. Sousa, M. M. M. Pinto. Synthesis of new proteomimetic quinazolinone alkaloids based on natural products and evaluation of their neuroprotective and antitumor effects. 10th Cambodian Chemical Society (CCS) symposium: Chemistry and Life, Phnom Penh, Cambodia, 4 -5 de October 2019.
– F. Durães, M. Pinto, E. Sousa. Design and synthesis of thioxanthones as potential bacterial efflux pump inhibitors. 12th European Workshop in Drug Design, Siena, Italy, May 19 – 24, 2019
– E. Sousa, S. Long, P. Boonpothong, D. Resende, F. Durães, A. Palmeira, A. M. S. Silva, A. Kijjoa, M. Pinto. Models from the sea: synthesis of potential new antibacterial agents. 2nd International Christmas Caparica Congress in Translational Chemistry – IC3TC-2017, Lisboa, Portugal, 4 a 7 de dezembro de 2017.
– Correia-da-Silva, M., Sousa, E., Almeida, J. R., Cunha, I., Vasconcelos, V., Pinto, M. Synthesis and Environmental Fate Evaluation of New Nature-Inspired Antifouling Compounds. OP Env Safe #3. 18th European Meeting on Environmental Chemistry (EMEC18), Porto, Portugal, November 26-29, 2017.
– E. Sousa, S. Long, P. Boonpothong, D. Resende, A. M. S. Silva, A. Kijjoa, M. Pinto. Marine-fungi natural products as models for new antibacterial agents. IL5. Transmediterranean Colloquium on Heterocyclic Chemistry (TRAMECH IX 2017), Fez, Morrocos, 22 -25 November 2017.
– I. Hrynchak, A. Reis-Mendes, A. Palmeira , M. L. Bastos, M. Pinto, V. Costa, E. Sousa. Old Pharmaceuticals with New Applications: the Case Studies of Lucanthone and Mitoxantrone. 3rd International Electronic Conference on Medicinal Chemistry, 1 -30 November 2017; (video key lecture).
– M. Correia-da-Silva, E. Sousa, J. R. Almeida, I. Cunha, V. Vasconcelos, M. Pinto. Synthesis and Environmental Fate Evaluation of New Nature-Inspired Antifouling Compounds. 18th European Meeting on Environmental Chemistry (EMEC18), Porto, Portugal, 26 -29 November 2017.
– M. Correia-da-Silva, E. Sousa, M. Pinto. One decade of synthesis of sulfated small molecules: from pharmaceutical to environmental applications. SUPA 2017 Conference, Birmingham, Reino Unido, 23 -25 April 2017
Electronic Communications – Internationals:
– Diana Resende, Mariana Almeida, Bruna Maciel, Helena Carmo, Isabel Almeida, José Sousa Lobo, Carlotta Pozzo, Sara Cravo, Gonçalo Rosa, Aida Kane-Pagès, Maria do Carmo Barreto, Madalena Pinto, Emília Sousa, New heterocyclic polyphenols with skin anti-aging potential. In Proceedings of the 5th International Electronic Conference on Medicinal Chemistry, 1-30 November, 2019. Doi:10.3390/ECMC2019-06362
– Liliana Raimundo, Sara Gomes, Joana Soares, Joana B. Loureiro, Mariana Leão, Helena Ramos, Madalena N. Monteiro, Juliana Calheiro, Nair Nazareth, Joana Almeida, Agostinho Lemos, Joana Moreira, Madalena Pinto, Petr Chlapek, Renata Veselsk, Emilia Sousa, Lucília Saraiva, Targeting neuroblastoma with a new inhibitor of the Tap73 interaction with MDM2 and mutant p53. In Proceedings of the 5th International Electronic Conference on Medicinal Chemistry, 1-30 November 2019. Doi:10.3390/ECMC2019-06305
– F. Durães, F. Barbosa, J. Freitas-Silva, P. Costa, M. Pinto, E. Sousa, In silico studies of bacterial efflux pump inhibition by thioxanthones and their synergistic antibacterial activity. In Proceedings of the 5th International Electronic Conference in Medicinal Chemistry, 1-30 November 2019. Doi:10.3390/ECMC2019-06300
– F. Carvalhal, A. R. Neves, A. Câmara, E. Sousa, M. Pinto, M. Correia-da-Silva. Biologically-active sulfated steroids: synthesis and state of-art. In Proceedings of the 4th International Electronic Conference in Medicinal Chemistry, 1-30 November 20182018.
– F. Durães; A. Palmeira; M. Pinto; E. Sousa, In silico studies of aminated thioxanthones: bacterial multidrug efflux pumps vs P-glycoprotein. In 4st International Electronic Conference on Medicinal Chemistry, 1-30 November 2018 (doi: 10.3390/ecmc-4-05598)
– Neves, A.; Correia-da-Silva, M.; Silva, P.; Ribeiro, D.; Sousa, E.; Bousbaa, H.; Pinto, M. Synthesis and Tumor Cell Growth Inhibitory Effects of New Flavonosides and Xanthonosides. 3rd International Electronic Conference on Medicinal Chemistry, November 1–30, 2017.
– W.W.M. Zin, C. Prompanya, C. Fernandes, S. Cravo, M.M.M. Pinto, A.Kijjoa, Chiral Liquid Chromatography in analysis of the stereochemistry of marine natural compounds: contribution for Medicinal Chemistry, 3rd International Electronic Conference on Medicinal Chemistry, November 1-30, 2017.
– A. R. Neves, M. Correia-da-Silva, P. M. A. Silva, D. Ribeiro, E. Sousa, H. Bousbaa, M. Pinto. Synthesis and Tumor Cell Growth Inhibitory Effects of New Flavonosides and Xanthonosides. 3st International Electronic Conference on Medicinal Chemistry, 1 a 30 de novembro de 2017
– A. Oliveira, V. Rodrigues, E. Sousa, M. H. Vasconcelos, M. Pinto, E. Sousa. “Curcumin derivatives as potential P-glycoprotein inhibitors: synthesis and stability studies”. 9º Meeting of Young Researchers of University of Porto (IJUP16), Porto, Portugal, 17-19 February, 2016.
– A. Lemos, A. S. Gomes, A. Palmeira, L. Saraiva, M. Pinto, E.Sousa.” Aminated derivatives for cancer therapy: Targeting p53 -MDM2 interaction with LEM2″. 9º Meeting of Young Researchers of University of Porto (IJUP16), Porto, Portugal, 17-19 February, 2016.
– Neves, A. R.; Sousa, E.; Pinto, M.; Correia-da-Silva, M. “Playing with hydrophilic and hydrophobic balance of bioactive sulfated compounds”. 9º Meeting of Young Researchers of University of Porto (IJUP16), Porto, Portugal, 17-19 February, 2016.
– Carvalho, C.; Duarte, B.; Marques, F.; Pinto, M.; Sousa, E.; Correia-da-Silva, M. “New triazole and non-triazole linked coumarin glucosides: synthesis, structure elucidation and biological activity”. 9º Meeting of Young Researchers of University of Porto (IJUP16), Porto, Portugal, 17-19 February, 2016. 42.
– Correia-da-Silva, M.; Almeida, J. R.; Cunha, I.; Sousa, E.; Pinto, M.; Vasconcelos, V. “Other face of the anticoagulant sulfated molecules coin: the promising of non-toxic antifouling agents”. First International Christmas Caparica Congress in Translational Chemistry – IC3TC-2015, Lisboa, Portugal,7-10 December 2015
– Raquel T. Lima, Diana Sousa, Ana Sara Gomes, Nuno Mendes, Rune Matthiesen, Madalena Pedro, Madalena M. Pinto, Emília Sousa, M. Helena Vasconcelos, “Antitumor activity of TXA1, an autophagy inducer which affects cholesterol localization”, 11 Encontro Nacional de Química Orgânica e 4 Encontro Nacional de Química Terapêutica, 1-3 December 2105, Porto, Portugal, MC-1pp 61
– J. Soares , R. Vieira, J. Neves, S. Reis, M. Pinto, C Azevedo, Carlos Afonso, “Lessons from the study of the binding mechanism of “hit” compounds to albumin: fluorescence and in silico experiments applied to xanthone derivatives”, 11 Encontro Nacional de Química Orgânica e 4 Encontro Nacional de Química Terapêutica, 1-3 December 2015, Porto, Portugal, MC-20, pp. 80
– Neves, A. R.; Sousa, E.; Pinto, M.; Correia-da-Silva, M.” Potential Orally-Active Heparin-Like Compounds: Synthesis and Anticoagulant Activity”. 1st International Electronic Conference on Medicinal Chemistry, 2-27 November 2015
– A. Lemos, A. S. Gomes, A. Palmeira, L. Saraiva, M. Pinto, E. Sousa. “Xantonas como fonte de inspiração para a obtenção de novos inibidores da interação p53/p73:MDM2”. 1º Encontro Científico do Núcleo de Estudantes de Química da Associação Académica de Coimbra, Coimbra, Portugal, 19-20 November 2015
– Sousa, E., Palmeira, A., Oliveira, A., Lopes-Rodrigues, V., Correia-da-Silva, M., Lima, R. T., Vasconcelos, M. H., Pinto, M. M., “Thioxanthones derivatives as dual inhibitors of P-glycoprotein and tumor cell growth”. W11-4. 51st Congress of the European Societies of Toxicology – EUROTOX 2015, Porto, Portugal, September 13-16, 2015.
– A. Lemos, P. Puthongking, A. Palmeira, A. Kijjoa, L. Saraiva, M. Pinto, E. Sousa. “Xanthone as a promising scaffold to develop new potential inhibitors of p53:MDM2 interaction”. IJUP’15 – 8º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 13-15 May 2015.
– A. Oliveira, E. Sousa, M. H. Vasconcelos, M. Pinto. “Synthesis of curcumin derivatives with potential to inhibit P-glycoprotein expression”. 8th edition IJUP – Meeting of Young Researchers of University of Porto, Porto, Portugal, 13-15 May 2015, A3, page 105.
– A. Lemos, P. Brandão, A. Palmeira, M. Pinto, L. Saraiva, E. Sousa. “A hybridization approach to obtain new xanthone derivatives as potential inhibitors of p53:MDM2 interaction”, III Encontro Nacional de Estudantes de Qumíca, Aveiro, Portugal, 27-29 March 2015
– A Gomes, Leão, M., Soares, J., Raimundo, R., Ramos H., Bessa C., Queiroz, G., Domingos, S., Palmeira A., Sousa, E., Pinto, M., Inga, A., Cidade, H., Saraiva, L. “A new inhibitor of the p53-MDM2 interaction derived from naturally occurring chalcones”. XLV Reunião Anual da Sociedade Portuguesa de Farmacologia, Lisboa, Portugal, 5-6 February 2015., S12C78.
– Renata Silva, Andreia Palmeira, Helena Carmo, Daniel Barbosa, Mariline Gameiro, Ana Gomes, Ana Mafalda Paiva, Sara Gomes, Emília Sousa, Madalena Pinto, Maria de Lourdes Bastos, Fernando Remião. “P-glycoprotein induction and activation by newly synthetized (thio)xanthones: in vitro and in silico studies”. XLV Reunião Anual da Sociedade Portuguesa de Farmacologia, Lisboa, Portugal, 5-6 February 2015.
– R. Silva, M. Gameiro, E. Sousa, H. Carmo, A. M. Paiva, A. Palmeira, D. Barbosa, M. Pinto, M. L. Bastos, F. Remião. “New thioxanthones and dihydroxylated xanthones as P-glycoprotein inducers/activators”. XLIV Reunião Anual da Sociedade Portuguesa de Farmacologia, Coimbra, Portugal, 5-7 February 2013, S11C1, 143.
– C. Pereira, I. Coutinho, V. Lopes-Rodrigues, M.P. Neves, R.T. Lima, A. Kijjoa, M. Pinto, H. Cidade, M.H.Vasconcelos, L. Saraiva.” Small-molecule activators of caspase-7 with potential antitumor activity identified using a yeast assay”. XLIII Reunião Anual da Sociedade Portuguesa de Farmacologia, XXXI Reunião de Farmacologia Clínica, XII Reunião de Toxicologia, Auditório ICBAS-FFUP, Porto, Portugal, 6-8 February 2013.
– Patrão, M.; Correia-da-Silva, M.; Pinto, M. M. M.; Sousa, E. “Synthesis of conjugates of polysulfated diosmin as potential orally-active anticoagulant agents”. OC. iMed – Innovating Medicine Conference, Lisbon, Portugal,October 12, 2013.
– J. Soares, C. Azevedo, A. Palmeira, D. Sousa, R. Lima, M. Pedro, M. Vasconcelos, C. Afonso, S. Reis, M.Pinto, “Multidimensional optimization of pyranoxanthones with potential antitumor activity”, 10ENQO-1SLB,Faculty of Pharmacy, University of Lisbon, Lisbon, Portugal, 04-06 September 2013.
– R.T. Lima, D. Sousa, H. Seca, A. Palmeira, A. M. Paiva, A. S. Gomes, V. Lopes-Rodrigues, J.E. Guimarães, M.X. Fernandes, M. Pedro, F. Cerqueira, M.M. Pinto, E. Sousa, M.H. Vasconcelos. “A new small molecule with antitumour and chemosensitizing potential as P-gp inhibitor”. COST Action CM1106 “Chemical Approaches to Targeting Drug Resistance in Cancer Stem Cells”, IPATIMUP, Porto, Portugal, 21-22 February 2013.
– N. Machado, M. Leão, A. Paiva, A. Palmeira, C. Pereira, L. Saraiva, M. Pinto, E. Sousa. “Virtual screening of a focused library of cell growth inhibitors to identify potential inhibitors of p53:MDM2 interaction”. IJUP’13 – 6º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 13-15 February 2013.
– J. Almeida, R. Castanheiro, J. Soares, C. Azevedo, C. Afonso, S. Reis, M. Pinto, “Evaluation of physicochemical properties of synthetic prenylated xanthone derivatives”, IJUP’13 – 6º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 13-15 February 2013.
– R. Vieira, D. Marques, J. Soares, C. Azevedo, A. Palmeira, Carlos M. M. Afonso, M. S. Reis, M. M. Pinto, “Binding mechanism of new potential antitumor molecules to albumin: a fluorescence and computational study applied to xanthone derivatives”, IJUP’13 – 6º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 13-15 February 2013.
Poster Communications (last 5 years)
469- Ramos, H., Resende D., Pinto M, Sousa E. Synthetic studies towards fumiquinazoline G. IJUP’20, Encontro de Investigação Jovem da Universidade do Porto, 13ª Edição, Reitoria da Universidade do Porto, 12- 14 February 2020.
467- R. Malta, L. Saraiva, P. Costa, M. Pinto, E. Sousa, J. Loureiro, M. Helena Amaral. Nanostructured lipid carriers (NLCs) containing LEM2 for topical treatment of skin cancer. IJUP’20, Encontro de Investigação Jovem da Universidade do Porto, 13ª Edição, Reitoria da Universidade do Porto, 12- 14 February 2020
466- A. Jesus, F. Durães, C. Afonso, M. Pinto, P. Costa, E. Sousa, H. Cidade. Marine bromophenol BDDE as a model for the synthesis of new chalcone derivatives with antibiotic synergic effects. IJUP’20, Encontro de Investigação Jovem da Universidade do Porto, 13ª Edição, Reitoria da Universidade do Porto, 12- 14 February 2020
465- Udomsak W., Resende D., Kijjoa A., Silva A.M.S., Pinto M, Sousa E. Synthesis of new proteomimetic quinazolinone alkaloids modified at the anthranilic and tryptophan moiety. 13th National Organic Chemistry Meeting – 6th National Medicinal Chemistry Meeting, 13ENQO-6ENQT, Aveiro, Portugal, 15- 17 January 2020.
464- R. Cristelo, C. Carvalho, B. Duarte, F. Marques, S. G. Monteiro, M. Morato, M. Pinto, E. Sousa, M. Correia da Silva. SCTC: a new orally active heparin mimetic. 13th National Organic Chemistry Meeting – 6th National Medicinal Chemistry Meeting, 13ENQO-6ENQT, Aveiro, Portugal, 15- 17 January 2020.
463- F. Durães, F. Barbosa, J. Freitas-Silva, M. Pinto, E. Pinto, P. Costa, E. Sousa. Design, synthesis and antimicrobial activity of potential modulators of bacterial efflux pumps. 13th National Organic Chemistry Meeting – 6th National Medicinal Chemistry Meeting, 13ENQO-6ENQT, Aveiro, Portugal, 15- 17 January 2020.
462- D. I. S. P Resende, B. A. S. Cruz, D. Ribeiro, P. P. M .A. Silva, H. Bousbaa, R. Silva, F. Remião, M. M. M. Pinto, E. Sousa. Xanthone derivatives as inhibitors of P-glycoprotein and of tumor cell growth: synthesis and biological evaluation. 13th National Organic Chemistry Meeting – 6th National Medicinal Chemistry Meeting, 13ENQO-6ENQT, Aveiro, Portugal, 15- 17 January 2020.
461- F. Durães, J. Moreira, A. R. Neves, F. Barbosa, J. Freitas-Silva, H. Cidade, M. Correia-da-Silva, M. Pinto, E. Pinto, P. Costa, E. Sousa. Antimicrobials from the Sea: Models for Innovative Agents to Revert Multidrug Resistance. Day of the Microbiology Laboratory, Faculty of Pharmacy, University of Porto, Porto, Portugal, November 15, 2019.
460- F. Durães, F. Barbosa, M. Pinto, E. Sousa. Unforeseen tandem Ullmann type C – N coupling and dehydrative cyclization of a thioxanthone and guanidine. XXVI Encontro Nacional da Sociedade Portuguesa de Química, Porto, Portugal, 24- 26 July 2019.
459- A. R. Neves, J. R. Almeida, V. Vasconcelos, M. Pinto, E. Sousa, E. R. Silva, M. Correia-da-Silva. Antifouling coatings with incorporated bile acid derivative. 4th MEETING OF THE CQU, Lisboa, Portugal, 16-19 July 2019.
458- A. R. Neves, J. Almeida, J. Antunes, E. Sousa, M. Pinto, V. Vasconcelos, M. Correia-da-Silva, Chemical Synthesis on Demand for Maritime Industry. Encontro com a Ciência e Tecnologia 2019, 8- 10 June 2019.
457- Gonçalves, C.; Neves, A.R.; Sousa, E.; Pinto, M.; Almeida, J.; Correia-da-Silva, M. Discovery of a new polyphenol acetylcholinesterase inhibitor.4ª Edição da Escola de Inverno de Farmácia, Porto, Portugal, 18 -27 March 2019.
456- Cristelo, R.; Correia-da-Silva M.; Sousa, E.; Pinto, M. M. Molecular modifications on coumarins: turning coumarins into factor Xa inhibitors? 4º Encontro da Escola de Inverno de Farmácia (EIF 2019), Porto, Portugal, 18 -27 March 2019.
455- Neves, A. R.; Freitas-Silva, J.; Pinto, E.; Martins da Costa, P.; Pinto, M.; Correia-da-Silva, M.; Sousa, E. Discovery of a cationic steroid active against multidrug-resistant bacteria and fungi. B1. 4ª Edição da Escola de Inverno de Farmácia, Porto, Portugal, 118 -27 March 2019.
454- F. Barbosa, F. Durães, E. Pinto, M. Pinto, E. Sousa. Synthesis of thioxanthone derivatives to revert drug resistances. 4ª Edição da Escola de Inverno de Farmácia, Porto, Portugal, 18 -27 March 2019.
453- Almeida, M. C.; Resende, D. I. S. P.; Pinto, M. M. M.; Almeida, I.; Sousa, E. Initial synthetic steps towards a polyoxygenated xanthone with promising anti-aging potential, Escola de Inverno de Farmácia, Faculdade de Farmácia, Universidade do Porto, 18 -27 March 2019.
452- Vallese, F.; Resende, D. I. S. P.; Sousa, E.; Pinto, M. M. M. Initial steps of the total synthesis of neofiscalin A, a natural antimicrobial alkaloid. 4ª Edição da Escola de Inverno de Farmácia – EIF2019, Faculdade de Farmácia da Universidade do Porto, 18 -27 March 2019.
451- A. Reis-Mendes, M. Duarte-Araújo, J. A. Duarte, S. Gonçalves-Monteiro, F. Carvalho, M. L. Bastos, E. Sousa, V. M. Costa. Evaluation of the toxicity induced by Doxorubicin in different age male CD-1 mice. MitoPorto, Porto Portugal, 13 July 2019.
450- Neves, A. R.; Gonçalves, C.; Almeida, J.; Vasconcelos, V.; Pinto, M.; Sousa, E.; Correia-da-Silva, M. Synthesis and antifouling screening of zosteric acid and gallic acid analogues. AMB47 XXV Encontro Galego-Português de Química, Santiago de Compostela, Sapin, 20 – 22 November 2019.
449- F. Durães, F. Barbosa, J. Freitas-Silva, S. Cravo, P. Costa, M. Pinto, E. Sousa. From the computer to the lab bench: design, synthesis and synergistic antibacterial activity of aminated thioxanthones. EUROPIN Summer School on Drug Design, Vienna, Austria, 15 – 20 September 2019.
448- Neves, A.R.; J. Freitas-Silva, J.; Pinto, E.; Martins da Costa, P.; Pinto, M.; Correia-da-Silva, M.; Sousa, E. Antimicrobial properties of a cationic steroid. P068. 6th EFMC Young Medicinal Chemist Symposium (EFMC-YMCS), Athens, Greece, 5 -6 September 2019.
447- Vilas-Boas, C., Carvalhal, F., Cravo, S., Sousa, E., Pinto, M., Silva, E. R., and Correia-da-Silva, M. Immobilization of a new eco-friendly antifouling agent in commercial marine coatings. BIOPROSP Conference, Tromso, Norway, 25- 27 February 2019.
446-Cristelo, R.; Correia-da-Silva, M.; Carvalho, C.; Sousa, E.; Pinto, M. M. Molecular modifications on hydroxycoumarins. 12th Meeting of young researchers of University of Porto (IJUP 2019) Porto, Portugal, 13-14-15 February, 2019.
445-Sousa, G.; Vilas-Boas, C.; Pinto, M; Sousa, E.; Correia-da-Silva, M. Environmental studies of two new synthetic xanthones. 12th Meeting of Young Researchers of University of Porto (IJUP19), Porto, Portugal, 13-15 February, 2019
444-Gonçalves,C.; Neves, A.R.; Sousa, E.; Pinto, M.; Vasconcelos, V.; Almeida, J.; Correia-da-Silva, M. In silico and in vivo evaluation of new synthetic antifouling compounds.12th Meeting of Young Researchers of University of Porto (IJUP19), Porto, Portugal, 13-15 February, 2019.
443-Alves, R.; Moreira, J.; Pereira, D.; Pinto, M.; Correia-da-Silva, M.; Cidade, H. 2,4-Dihydroxy-3-propylacetophenone derivates as synthetic intermediates: synthesis and structure elucidation. 12th Meeting of Young Researchers of University of Porto (IJUP 2019), Porto, Portugal, 13-15 February, 2019
442- A. Jesus, D. Pereira, C. Afonso, M. Pinto, H. Cidade, Marine Bromophenols as models for the synthesis of halogenated chalcone derivatives. 12º Encontro de Jovens Investigadores da Universidade do Porto, Porto, Portugal, February 13-15, 2019
441-F. Barbosa, F. Durães, E. Pinto, M. Pinto, E. Sousa. Synthesis of thioxanthones as potential inhibitors of efflux pumps. 12.º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, February 13-15, 2019
440- Almeida, M. C.; Pinto, M. M. M.; Almeida, I.; Resende, D. I. S. P.; Sousa, E. “Synthetic pathway towards a polyoxygenated xanthone with anti-aging potential”, IJUP, Encontro de Investigação Jovem da Universidade do Porto, 12ª Edição, Faculdade de Medicina da Universidade do Porto, 13-15 fevereiro 2019
439- Martins, E.; Barbosa, D.; Sousa, E.; Resende, D. I. S. P.; Pinto, M. M. M.; Remião, F.; Silva, R. “Newly synthetized xanthonic derivatives as potential P-glycoprotein modulators: a strategy to fight Alzheimer’s disease”, IJUP, Encontro de Investigação Jovem da Universidade do Porto, 12ª Edição, Faculdade de Medicina da Universidade do Porto, 13-15 fevereiro 2019
438- Silva, V.; Silva, R.; Martins, E.,; Resende, D. I. S. P.; Pinto, M. M. M.; Remião, F.; Sousa, E.; Rocha-Pereira, C. “Newly synthetized xanthones as potential P-glycoprotein modulators at the intestinal barrier: in vitro and ex vivo studies”, IJUP, Encontro de Investigação Jovem da Universidade do Porto, 12ª Edição, Faculdade de Medicina da Universidade do Porto, 13-15 fevereiro 2019
437-Romanholo, M. N.; Barbosa, A. I.; Resende, D. I. S. P.; Lima, S. A. C.; Pinto, M. M. M.; Reis, S.; Sousa, E. “Marine nature as a source for cancer therapy: xanthone loaded fucoidan/chitosan nanoparticles”, IJUP, Encontro de Investigação Jovem da Universidade do Porto, 12ª Edição, Faculdade de Medicina da Universidade do Porto, 13-15 February 2019
436- J. C. Costa, Daniela R. P. Loureiro, J. X. Soares, A. F. Magalhães, C. M. G. Azevedo, M. M.M. Pinto, C. M.M. Afonso, Synthesis of marine derived xanthone with antimicrobial activity, 12º Encontro de Jovens Investigadores da Universidade do Porto, Porto, Portugal, February 13-15,2019
435- B. Silva, C. Fernandes, M. Pinto, P. Guedes, F. Remião, HPLC enantioresolution of pentedrone and in vitro cytotoxicity studies, SPF2018, Sociedade Portuguesa de Farmacologia, Lisbon, Portugal, February 5-7, 2018.
434- A. R. Franco, D. Pereira, M. Correia da Silva, M. Pinto, H. Cidade, “Synthesis of triazole linked chalcone derivatives by Click Chemistry”, IJUP’18 – 11th Meeting of Young Researchers of U. Porto, University of Porto, Porto, Portugal, February 7-9, 2018, 13986.
433- A. R. Tavares, A. R. Neves, E. Sousa, M.M. Pinto, M. Correia-da-Silva, Synthesis of a new xanthone by “click chemistry”. IJUP’18 – 11th Meeting of Young Researchers of U. Porto, University of Porto, Porto, Portugal, February 7-9, 2018.
432- Álvaro F. Magalhães, J. Soares, D. Loureiro, S. Cravo, C. Azevedo, C. Afonso, M. Pinto; “Marine xanthones: synthesis and in silico ADME profile”; 3ª Edição da Escola de Inverno de Farmácia – EIF2018, Porto, March 9, 2018.
431- Álvaro F. Magalhães, J. Soares, D. Loureiro, J. Pinto, S. Cravo, C. Azevedo, C. Afonso, M. Pinto; “Synthesis and in silico biophysicochemical properties of marine xanthones and derivatives; 12th National Organic Chemistry Meeting & 5th National Medicinal Chemistry Meeting, Coimbra, January 17-19, 2018.
430- C. Fernandes, M. L. Carraro, C. Veloso, M. E. Tiritan, S. Marques, P. M.A. Silva, H. Bousbaa, A. M.S. Silva, M. M.M. Pinto, “Carboxyxanthone derivatives: synthesis and effect on human tumor cell lines”, 12º Encontro Nacional de Química Orgânica e 5º Encontro de Química Terapêutica, Coimbra,Portugal, 17-19 January, 2018, p. 90.
429- C. Leite, P. Barbosa, K. Maslowska, B. Polónia, J. Ribeiro, Y.Z. Phyo, C. Fernandes, M.E. Tiritan, A. Kijjoa, M.M.M. Pinto, Synthesis of xanthone derivatives: important chemical substrates to obtain bioactive compounds, Escola de Inverno de Farmácia, 3ª edição, 7-15 March, 2018.
428- C. Machado, D. Almeida, J. Moreira, P. M. A. Silva, H. Bousbaa, M. Pinto, H. Cidade, Chalcone Derivatives: Synthesis and Antitumor Activity Evaluation, IJUP’18 – 11th Meeting of Young Researchers of U. Porto, University of Porto, Porto, Portugal, February 7-9, 2018, 13972.
427- C.M. Machado, P. Pinto, D. Almeida, P. M. A. Silva, J. Moreira, J. Salvador, M. Pinto, H. Bousbaa, H. Cidade, “Chalcone Derivatives with Potential Antitumor Activity: Synthesis and Antimitotic Activity Evaluation”, 3ª Edição da Escola de Inverno de Farmácia, 7-15th March 2018, Porto, Portugal.
426- D. Loureiro, J. Soares, S. Cravo, C. Azevedo, M. Pinto, C. Afonso; “Synthesis of two important building blocks of antimicrobial marine xanthones”; 3ª Edição da Escola de Inverno de Farmácia – EIF2018, Porto, March 10, 2018
425- D. Pereira, B.T. Martins, M. Correia da Silva, H. Cidade, M. Pinto, “Synthesis of Triazole Linked Flavonoid Glycosides by Click Chemistry”, 12º Encontro Nacional de Química Orgânica e 5º Encontro de Química Terapêutica, Coimbra, 17-19 Janeiro 2018
424- D. Pereira, M. Correia-da-Silva, B. T. Martins, A. R. Franco, M. Pinto, H. Cidade, “Synthesis of new flavonoid glycosides with a triazole Moiety”, 3ª Edição da Escola de Inverno de Farmácia, 7-15th March 2018, Porto, Portugal.
423- F. Carvalhal, J. Almeida, E. Sousa E, C. Fernandes, V. Vasconcelos, M. Pinto, M. Correia-da-Silva, Synthesis of new bioinspired antifouling agents, 12th National Organic Chemistry Meeting & 5th National Medicinal Chemistry Meeting, 17-19 January, 2018.
422- F. Carvalhal, M. Correia-da-Silva, E. Sousa, M. Pinto, Synthesis of 3-(2,3,4,6-tetra-sulfate-O-β-D-glucopyranosyl)xanthone: a potential new anticoagulant compound. P. J.2. 3ª Edição da Escola de Inverno de Farmácia, Porto, Portugal, March 7-15, 2018.
421- H. Cidade, C. Machado, P. Pinto, J. D. Almeida, P. Brandão, J. Loureiro, J. Salvador, P. Silva, L. Saraiva, H. Bousbaa, M. Pinto, “New Chalcone Derivatives: Synthesis and Antitumor Activity Evaluation”, 12º Encontro Nacional de Química Orgânica e 5º Encontro de Química Terapêutica, Coimbra, 17-19 Janeiro 2018, P99, pp.195.
420- J. P. Vilares, G. Faria, Á. F. Magalhães, D. Loureiro, J. Soares, C. Azevedo, M. Pinto, C. Afonso; “Synthesis of xanthone derivatives with potential antimicrobial activity”; 11th Meeting of Young Researchers of University of Porto (IJUP18), Porto, Portugal, February 7-9, 2018.
419- J. Ribeiro, C. Fernandes, M.E. Tiritan, A.M.S. Silva, M.M.M. Pinto, Development of chiral stationary phases based on small molecules and polymeric derivatives for enantioseparation of chiral drugs, Escola de Inverno de Farmácia, 3ª edição, 7-15 March, 2018.
418- J.P. Carmo, C. Fernandes, M.E. Tiritan, C. Afonso, M.M.M. Pinto, Enantioresolution of bioactive compounds on human serum albumin stationary phase, Escola de Inverno de Farmácia, 3ª edição, 7-15 March, 2018
417- Y.Z. Phyo, S. Cravo, M.E. Tiritan, A. Kijjoa, M.M.M. Pinto, C. Fernandes, Macrocyclic glycopeptide antibiotics: application as chiral selectors for enantioseparation of bioactive compounds, Escola de Inverno de Farmácia, 3ª edição, 7-15 March, 2018.
416- M. E. Tiritan, H. Oliveira, V. Barbosa, P. De Marco, C. Fernandes, A. M.S. Silva, M. M.M. Pinto“Synthesis of new chiral derivatives of xanthones coupled with proteinogenic amino acids”, 12º Encontro Nacional de Química Orgânica e 5º Encontro de Química Terapêutica, Coimbra, Portugal, 17-19 January, 2018, P20.
415- P. Brandão, J. B. Loureiro, S. Carvalho, M. H. Hamadou, S. Cravo, J. Moreira, D. Pereira, M. Pinto, L. Saraiva, H. Cidade, “Prenylchalcones with potent antiproliferative activity targeting p53 pathway: synthesis and biological activity evaluation”, 3ª Edição da Escola de Inverno de Farmácia, 7-15th March 2018, Porto, Portugal.
414- J. Ribeiro, C. Fernandes, M.E. Tiritan, A.M.S. Silva, M.M.M. Pinto, Preparation of a new chiral stationary phase for liquid chromatography based on a small molecule, 10º Encontro Nacional de Cromatografia, Bragança, 4-6 December, 2017.
413- J.P. Carmo, C. Fernandes, M.E. Tiritan, C. Afonso, M.M.M. Pinto, Liquid chromatography enantioseparation of xanthone derivatives on a human serum albumin stationary phase, 10º Encontro Nacional de Cromatografia, Bragança, 4-6 December, 2017.
412- Y.Z. Phyo, A. Palmeira, S. Cravo, M.E. Tiritan, A.Kijjoa, M.M.M. Pinto, C. Fernandes, Enantiomeric separation and chiral recognition mechanisms of different macrocyclic glycopeptide-based chiral stationary phases, 10º Encontro Nacional de Cromatografia, Bragança, 4-6 December, 2017.
411- C. Vilas-Boas, S. Cravo, E. Sousa, M. Pinto, M. Correia-da-Silva. Development and validation of an HPLC method for quantification of the biocide Econea®. 10º Encontro Nacional de Cromatografia (10ENC), Bragança, Portugal, 4 – 6 December 2017.
410- S. Long, D. Resende, A. Kijjoa, A. M. S. Silva, A. Pina, T. Fernández-Marcelo, M. H. Vasconcelos, E. Sousa, M. Pinto. Antitumor Activity of Quinazolione Alkaloids-Inspired in Marine Products. XXV Encontro Nacional Sociedade Portuguesa de Química, Lisboa, Portugal, 16 – 19 July 2017.
409- P. Boonpothong, D. Resende, A. Kijjoa, E. Sousa, M. Pinto, Progress towards neofiscalin A synthesis, a potent antibacterial agent, XXV Encontro Nacional Sociedade Portuguesa de Química, Lisboa, Portugal, 16 – 19 July 2017.
408- A. Reis-Mendes, S. Gomes, R. Carvalho, F. Carvalho, F. Remião, M. Pinto, M. L. Bastos, E. Sousa, V. M. Costa. Mitoxantrone and its naphthoquinoxaline metabolite: a comparative study in differentiated h9c2 cells. SPF 2016 – XLVII Reunião Anual Da Sociedade Portuguesa De Farmacologia, XXXV Reunião De Farmacologia Clínica, XVI Reunião de Toxicologia, Coimbra, Portugal, 2- 4 February 2017
407- Coutinho Alves, A.D.; Sousa, E.; Pinto, M.M.M.; Correia da Silva, M.; Ferreira, D.; Costa, P. Development of an HPLC method for the quantification of a new glycosylated xanthone with cell growth inhibitory activity. 10th Meeting of Young Researchers of University of Porto (IJUP17), Porto, Portugal, 8- 10 February 2017
406- Carvalhal, F.; Sousa, E.; Neves, A. R.; Correia-da-Silva, M.; Pinto, M. Synthesis and structural elucidation of 3,4-dihydroxyxanthone derivatives. 10th Meeting of Young Researchers of University of Porto (IJUP17), Porto, Portugal, 8- 10 February 2017
405- Vilas-Boas, C.; Cravo, S.; Sousa, E.; Pinto, M.; Correia-da-Silva, M. Sea-water solubility and degradation studies of sulfated small molecules. 10th Meeting of Young Researchers of University of Porto (IJUP17), Porto, Portugal, 8- 10 February 2017
404- Martins, B. T.;Pereira, D.; Correia-da-Silva, M.; Cidade, H.; Pinto, M. Synthesis of potential bioactive flavone derivatives. 10th Meeting of Young Researchers of University of Porto (IJUP17), Porto, Portugal, 8- 10 February 2017.
403- Confraria, C.; Almeida, I. F.; Pinto, M.; Sousa, E.; Correia-da-Silva, M. Synthesis of a Water Soluble Resveratrol Derivative for Skin Care Formulations. 10th Meeting of Young Researchers of University of Porto (IJUP17), Porto, Portugal, 8- 10 February 2017
402- I. Hrynchak, E. Sousa, M. L. Bastos, M. Pinto, V. M. Costa. Synthesis and characterization of the main metabolites of mitoxantrone. 10º Meeting of Young Researchers of University of Porto (IJUP17), Porto, Portugal, 8- 10 February 2017
401- P. Boonpothong, D. Resende, A. Kijjoa, E. Sousa, M. Pinto. Synthetic Studies Towards Neofiscalin A, a Potent Antibacterial Agent. 10º Meeting of Young Researchers of University of Porto (IJUP17), Porto, Portugal8- 10 February 2017
400- N. Lopes, S. Long, D. Resende, A. Kijjoa, A. Silva, M. Pinto, E. Sousa. Synthetic strategies for fiscalin B and analogues. 10º Meeting of Young Researchers of University of Porto (IJUP17), Porto, Portugal, 8- 10 February 2017
399- A. Reis-Mendes, S. Gomes, R. Carvalho, F. Carvalho, F. Remião, M. Pinto, M. L. Bastos, E. Sousa, V. M. Costa. Mitoxantrone and its naphthoquinoxaline metabolite: a comparative study in differentiated h9c2 cells. SPF 2016 – XLVII Reunião Anual Da Sociedade Portuguesa De Farmacologia, XXXV Reunião De Farmacologia Clínica, XVI Reunião de Toxicologia, Coimbra, Portugal, 2 – 4 February 2017.
398- C. Leite, C. Fernandes, M.E. Tiritan, M. Pinto, Total synthesis and structure elucidation of 3-carboxymethoxyxanthone, IJUP 2017, 10th Meeting of Young Researches of University of Porto, Encontro de Investigação Jovem da Universidade do Porto, 8-10 February, 2017.- J. Ribeiro, C. Fernandes, M.E. Tiritan, M.M.M. Pinto, Synthesis and structure elucidation of carboxyxanthone derivative, IJUP 2017, 10th Meeting of Young Researches of University of Porto, 8-10 February, 2017.
397- H. Ribeiro, V. Barbosa, A.S. Malheiro, S. Dias, M.E. Tiritan, A.M.S. Silva, C. Fernandes, M.M.M. Pinto, Strategy for synthesis of enantiomerically pure xanthones – amino acid derivatives, IJUP 2017, 10th Meeting of Young Researches of University of Porto, 8-10 February, 2017.
396- C. M. Machado, J. Moreira, A. Bartzoka, H. Cidade, M. Pinto, “Chalcone Isosteres: Synthesis and Structure Elucidation”, IJUP 2017 -10th Meeting of Young Researchs of U. Porto, Porto, Portugal, 8-10 February, 2017.
395- A. R. Neves, J. R. Almeida, J. Antunes, V. Vasconcelos, E. Sousa, M. Pinto, M. Correia-da-Silva, “Synthesis of Steroid Derivatives with Anti-microfouling and Anti-macrofouling Properties.” PP Env Safe #16. 18th European Meeting on Environmental Chemistry (EMEC18), Porto, Portugal, November 26-29, 2017.
394- C. Fernandes, M.L. Carraro, M.E. Tiritan, S. Marques, P.M.A. Silva, H. Bousbaa, A.M.S. Silva, M. Pinto, “Synthesis, enantiomeric purity evaluation and enantioselectivity study on human tumor cell lines of new chiral derivatives of xanthones”, EFMC-ASMC’17, Vienna, Austria, 27-31 August 2017, pp. 159.
393- D. Resende, E. Sousa, M. M. M. Pinto, “Synthesis of xanthone derivatives based on marine natural models with promising biological activities“, 9th Trans Mediterranean Colloquium on Heterocyclic Chemistry (TRAMECH IX), Fes, Morocco, 22-25 November 2017 (PP129).
392- D. Resende, S. Long, P. Boonpothong, A. M. S. Silva, A. Kijjoa, E. Sousa, M. M. M. Pinto, “Synthetic strategies for the synthesis of quinazoline alkaloid derivatives with promising biological activities”, 20th European Symposium on Organic Chemistry (ESOC 2017), Cologne, Germany, 2-6 July 2017, LM002.
391- M. Correia-da-Silva, J.R. Almeida, D. Pereira, J. Moreira, V. Vasconcelos, M. Pinto, H. Cidade, “Synthesis of chalcone derivatives and anti-settlement activity against Mytilus galloprovincialis Larvae”, 18th European Meeting on Environmental Chemistry (EMEC), Porto, Portugal, 26-29 November 2017, PP Env Safe #6, pp. 314.
390- Y.Z. Phyo, C. Fernandes, M.E. Tiritan, S. Cravo, A.M.S. Silva, A. Kijjoa, M.M.M. Pinto, Analytical applications of xanthone derivatives as chiral selectors for liquid chromatography, Transmediterranean Colloquium on Heterocyclic Chemistry (TRAMECH IX 2017), Fez, Morocco, 22-25 November, 2017
389- S. Long, N. Thongdee, J.B. Loureiro, M.M. Pinto, P. Puthongking, L. Saraiva, E. Sousa. Aminocarbazole alkaloid derivatives as potential modulators of p53mutants, 18th International Conference on MedicinalChemistry & Targeted Drug Delivery, Dallas, USA, 6-8 December, 2017.
388- N. Lopes, S. Long D. Resende A. Kijjoa A. Silva A. Pina, T. Fernández-Marcelo, M. H. Vasconcelos, M. Pinto, E. Sousa. Synthesis and tumor cell growth inhibitory effects of the marine product analogues of fiscalin B, 12th Young European Scientist Meeting (YES2017), Porto, Portugal, 14 -17 de September 2017.
387- I. Hrynchak, E. Sousa, M. L. Bastos, M. Pinto, and V. M. Costa. Studies towards the synthesis of dicarboxylic acid metabolite of mitoxantrone. 12th Young European Scientist Meeting (YES2017), Porto, Portugal, 14 -17 de September 2017.
386- H. Cidade, P. Brandão, S. Carvalho, J. Moreira, D. Pereira, S. Cravo, J. Soares, L. Saraiva, M. Pinto, “Potential inhibitors of the p53-MDM2 interaction: synthesis and biological evaluation”, EFMC-ASMC17-VII International Symposium on Advances in Synthetic and Medicinal Chemistry, Vienna, Austria, 27-31 August 2017
385- Correia-da-Silva, M.; Neves, A.R.; Carvalho, C.; Câmara, A.; Sousa, E.; Pinto, M. Synthesis of natural and non-natural sulfated compounds: challenges and opportunities. P-018. Terceiro Simpósio Ibero-americano de Química Orgânica (SIBEAQO-III), Porto, Portugal, September 23-26, 2016.
384- Almeida, J. R.; Correia-da-Silva, M.; Sousa, E.; Pinto, M.; Vasconcelos, V.; Cunha, I. Antifouling properties of nature-inspired synthetic compounds. International Congress on Marine Corrosion and Fouling 18th ICMCF, Toulon, France, June 19-24, 2016.
383- A. Lopes, R. Silva, C. Fernandes, F. Remião, M. Pinto, E. Sousa. Chiral Thioxanthones as Promising P glycoprotein Modulators. 5th Portuguese Young Chemists Meeting and 1st European Young Chemists Meeting, Guimarães, Portugal. 26-29 April 2016
382- A. Lopes, S. Long, C. Fernandes, M. Pinto, E. Sousa. Synthesis of new tioxanthone derivatives. 9th Meeting of Young Researches of University of Porto, Porto, Portugal. 17-19 February 2016.
381- Câmara, A.; Neves, A. R.; Pinto, M.; Sousa, E.; Correia-da-Silva, M. Synthesis of a natural marine antifouling compound. 9º Meeting of Young Researchers of University of Porto (IJUP16), Porto, Portugal, 17-19 February, 2016.
380- Gatarz, S.; Neves, A. R.; Sousa, E.; Pinto, M.; Correia-da-Silva, M. Scale-up synthesis of promising antifouling compounds. 9º Meeting of Young Researchers of University of Porto (IJUP16), Porto, Portugal,17-19 February, 2016.
379- C. Fernandes, A. Santos, J. Soares, S. Cravo, M.E. Tiritan, C. Afonso, M. Pinto ,An example of the key role of HPLC in Medicinal Chemistry: determination of lipophilicity of a xanthone derivatives library, 11 Encontro Nacional de Química Orgânica e 4 Encontro Nacional de Química Terapêutica, 1-3 December 2105, Porto, Portugal, P-10, pag 100
378 – E. Sousa, A. Lemos, A. S. Gomes, A. Palmeira,L. Saraiva,M. Pinto, Xanthone as a valuable scaffold to identify new promising antitumor agents via inhibition of p53/p73:MDM2 interaction, 11 Encontro Nacional de Química Orgânica e 4 Encontro Nacional de Química Terapêutica, 1-3 December 2105, Porto, Portugal, P-14, pag. 104
377 – Cidade H, Pereira D, Lima RT, Palmeira A, Seca H, Soares J, Gomes, Raimundo L, Maciel C, Sousa E, Vasconcelos MH, Saraiva L, Pinto M, Promising Chalcone Derivatives as New Inhibitors of p53-MDM2 Interaction, 11 Encontro Nacional de Química Orgânica e 4 Encontro Nacional de Química Terapêutica, 1-3 December 2105, Porto, Portugal, P-16, pag. 104
376 – Cruz, M. I. S., Cravo, S. M., Cidade, H. and Pinto, M, Xanthone and Flavone Derivatives as Potential Dual Agents for Alzheimer’s Disease, 11 Encontro Nacional de Química Orgânica e 4 Encontro Nacional de Química Terapêutica, 1-3 December 2105, Porto, Portugal, P-17, pag 107
375 – Marta Correia da Silva, Catarina Carvalho, Emília Sousa, Madalena Pinto, Synthesis of Innovative Anticoagulant Hybrids, 11 Encontro Nacional de Química Orgânica e 4 Encontro Nacional de Química Terapêutica, 1-3 December 2105, Porto, Portugal, P-26, pag. 116
374 – Vanessa Lopes-Rodrigues, Ana Oliveira, Marta Correia-da-Silva, Madalena Pinto, Raquel T.Li¬ma, Emília Sousa, M. Helena Vasconcelos, A new curcumin derivative with more potent antitumor and anti-P-glycoprotein activity than curcumin, 11 Encontro Nacional de Química Orgânica e 4 Encontro Nacional de Química Terapêutica, 1-3 December 2105, Porto, Portugal, P-62, pP. 152
373- Neves, A. R.; Correia-da-Silva, M.; Sousa, E.; Pinto, M. Heparin-like small-molecules: reaching oral bioavailability. P28. EFMC Young Medicinal Chemist Symposium, Antwerp, Belgium, 17 September, 2015.
372 – M.L. Carraro, A.S. Silva, C. Fernandes, M.E. Tiritan, A.M.S. Silva and M. Pinto, “Promising new antitumor chiral derivatives of xanthones: synthesis and evaluation of enantiomeric purity by HPLC”, YES METTING, Young European Scientist Meeting, Porto, Portugal, 17-20 September 2015.
371- M.L. Carraro, A.S. Silva, C. Veloso, M.E. Tiritan, A.M.S. Silva, M. Pinto and C. Fernandes, “Promising bioactive chiral derivatives of xanthones using carboxyxanthones as chemical substracts”, II Simposio de Jóvens Investigadores de la Sociedad Española de Química Terapéutica, Madrid, Spain, 12 June 2015.
370 – C. Fernandes, L. Carraro, A. S. Silva, C. Veloso, M. E. Tiritan, A. M. S. Silva, M. Pinto, “New bioactive chiral derivatives of xanthones: synthesis and optimization of their xanthonic building block”, 7th Spanish-Portuguese-Japanese Organic Chemistry Symposium, Seville, Spain, 23-26 de June 2015.
369 – A. Santos, M.E. Tiritan, S. Cravo, M. Pinto and C. Fernandes, “RP-HPLC evaluation of the lipophilicity of chiral derivatives of xanthones: correlation between chromatographic and theoretical methods”, HPLC 2015, Geneva, Switzerland, 21-25 June 2015.
368 – Rocha, V., Marques, C., Contente, S., Sousa, M.E., Palmeira, A., Correia-da-Silva, M., Pinto, M., Sousa Lobo, J.M., Almeida, I.F. Novel resveratrol derivative for skin care. V Congresso Nacional de Ciências Dermatocosméticas, Porto, Portugal, 15 May, 2015.
367 – A. Lemos, P. Puthongking, A. Palmeira, A. Kijjoa, L. Saraiva, M. Pinto, E. Sousa. “Xanthone as a promising scaffold to develop new potential inhibitors of p53:MDM2 interaction”. IJUP’15 – 8º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 13-15 de Maio de 2015.
366 – A. Oliveira, E. Sousa, M. H. Vasconcelos, M. Pinto. Synthesis of curcumin derivatives with potential to inhibit P-glycoprotein expression. 8th edition IJUP – Meeting of Young Researchers of University of Porto, Porto, Portugal, 13-15 May 2015, A3, page 105.
365 – Ana R. Moreira, Gabriela Moreira, Agostinho Lemos, Emília Sousa,, Madalena M. M. Pinto, Paulo Costa, Domingos Ferreira. Synthesis of a xanthonic compound with antitumor activity and development of proliposomes as its delivery system.8º Encontro de Jovens Investigadores da Universidade do Porto (IJUP15), Porto, Portugal, 13-15 maio, 2015.
364 – A. Reis-Mendes, A.S. Gomes, R.A. Carvalho, F. Remião, F. Carvalho, M. Pinto, M.L. Bastos, E. Sousa, and V.M. Costa. The cardiotoxicity of mitoxantrone: A comparative in vitro study between mitoxantrone and its naphthoquinoxaline metabolite. 8º Encontro de Jovens Investigadores da Universidade do Porto (IJUP15), Porto, Portugal, 13-15 maio, 2015.
363 – H. Ramos, S. Gomes, M. Leão, J. Soares, L. Raimundo, G. Queiroz, P. Brandão, M. Pinto, E. Sousa and L. Saraiva. LEM2: a new small molecule inhibitor of the p73-MDM2 interaction. 8º Encontro de Jovens Investigadores da Universidade do Porto (IJUP15), Porto, Portugal, 13-15 maio, 2015.
362 – I. Nogueira, A. Oliveira, P. Melo, F. Ferreira, M. Pinto, E. Sousa. Synthetic and natural dyes as models for bioactive compounds. 8thedition IJUP – Meeting of Young Researchers of University of Porto, Porto, Portugal, 13-15 May 2015, Poster Session, page 278.
361- Moreira, J.; Castro, M.; Fernandes, C.; Correia da Silva, M.; Sousa, E.; Cidade, H.M.; Afonso, C. M.; Pinto, M.; Vasconcelos, V.; Urbatzka R. Plant-derived and synthetic compounds affect the proliferation and metabolic activity of 3T3-L1 preadipocytes. IJUP 2015 – 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 13-15 May 2015.
360 – Carvalho, C.; Correia-da-Silva, M.; Duarte, B.; Marques, F.; Sousa, E.; Pinto, M. Sulfated coumarin glucosides: synthesis and anticoagulant activity. IJUP 2015 – 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 13-15 May 2015.
359 – Neves, A. R.; Correia-da-Silva, M.; Sousa, E.; Pinto, M. Synthesis of a sulfated flavonoid – deoxycholic acid conjugate as a potential orally-active antithrombotic agent. IJUP 2015 – 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 13-15 May 2015.
358 – Zovinec, M.; Neves, A. R.; Correia-da-Silva, M.; Sousa, E.; Pinto, M. Carboxymethylation of flavonoids: synthesis, purification and structure elucidation. IJUP 2015 – 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 13-15 May 2015.
357 – Guerra, A.C.; Correia-da-Silva, M.; Rachão, A.; Veiga, H.; Neves, C.; Sousa, E.; Pinto, M.M.M.; Soares, R.; Negrão, R. Effects on Endothelial Cells and Angiogenesis of Structurally-Diverse Xanthones. IJUP 2015 – 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 13-15 May 2015.
356 -.A.S. Silva, M.E. Tiritan, A.M.S. Silva, M. Pinto and C. Fernandes, “Synthesis of promising bioactive chiral derivatives of xanthones with two stereogenic centres”, IJUP 2015 – 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 13-15 May 2015.
355 – C. Veloso, M. E. Tiritan, A.M.S. Silva, M. Pinto and C. Fernandes, “Synthesis and structural elucidation of a new carboxyxanthone”, IJUP 2015 – 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 13-15 May 2015.
354 – M.L. Carraro, M.E. Tiritan, A.M.S. Silva, M. Pinto and C. Fernandes, “Total synthesis of fluorinated chiral derivatives of xanthones”, IJUP 2015 – 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 13-15 May 2015.
353 – J. Moreira, M. Castro, C. Fernandes, M. Correia da Silva, E. Sousa, H.M. Cidade, C. M. Afonso,M. Pinto, V. Vasconcelos and R. Urbatzka, “Plant-derived and synthetic compounds affect the proliferation and metabolic activity of 3T3-L1 preadipocytes”, IJUP 2015 – 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 13-15 May 2015.
352 – B. Silva, C. Fernandes, M. Pinto, P. Guedes de Pinho and F. Remião, “Chiral HPLC enantioresolution of synthetic cathinones “Legal Highs”, IJUP 2015 – 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 13-15 May 2015.
351- Álvaro Santos, Maria Elizabeth Tiritan, Sara Cravo, Madalena pinto, Carla Fernandes, RP_HPLC evaluation of the lipophilicity of chiral derivatives of xanthones: correlation betweeen chromatographic and theoretical methods, HPLC 2015, Geneve, Swityzerland 21-25 June, 2015
350- A. Oliveira, E. Sousa, M. H. Vasconcelos, M. Pinto. ” Curcumin, a valuable model for novel therapeutic agents: synthesis and biological activities of curcumin derivatives “, III Encontro Nacional de Estudantes de Qumíca, Aveiro, Portugal, 27-29 de Março de 2015.
349- A. Lemos, P. Brandão, A. Palmeira, M. Pinto, L. Saraiva, E. Sousa. “A hybridization approach to obtain new xanthone derivatives as potential inhibitors of p53:MDM2 interaction”, III Encontro Nacional de Estudantes de Qumíca, Aveiro, Portugal, 27-29 de Março de 2015, P9.
348-Neves, A.R.; Correia-da-Silva, M.; Sousa, E.; Duarte, P.; Silva, P; Bousbaaa, H.; Pinto, M. Acetylated flavonoids and xanthones: synthesis and screeningfor antitumor activity. III Encontro Nacional de Estudantes de Química, Aveiro, Portugal, Março 27-29, 2015.
347-Neves, A. R.; Correia-da-Silva, M.*; Sousa, E.; Pinto, M. Synthesis of a sulfated flavonoid – deoxycholic acid conjugate as a potential orally-active antithrombotic agent. 8º Encontro de Jovens Investigadores da Universidade do Porto (IJUP15), Porto, Portugal, 13-15 maio, 2015.
346-Zovinec, M.; Neves, A. R.; Correia-da-Silva, M.; Sousa, E.; Pinto, M. Carboxymethylation of flavonoids: synthesis, purification and structure elucidation. 8º Encontro de Jovens Investigadores da Universidade do Porto (IJUP15), Porto, Portugal, 13-15 maio, 2015.
345-Guerra, A.C.; Correia-da-Silva, M.; Rachão, A.; Veiga, H.; Neves, C.; Sousa, E.; Pinto, M.M.M.; Soares, R.; Negrão, R. Effects on Endothelial Cells and Angiogenesis of Structurally-Diverse Xanthones. 8º Encontro de Jovens Investigadores da Universidade do Porto (IJUP15), Porto, Portugal, 13-15 maio, 2015.
344-Moreira, J.; Castro, M.; Fernandes, C.; Correia da Silva, M.; Sousa, E.; Cidade, H.M.; Afonso, C. M.; Pinto, M.; Vasconcelos, V.; Urbatzka R. Plant-derived and synthetic compounds affect the proliferation and metabolic activity of 3T3-L1 preadipocytes. 8º Encontro de Jovens Investigadores da Universidade do Porto (IJUP15), Porto, Portugal, 13-15 maio, 2015.