Conferences , Oral and Poster Comunications

Plenaries

– Madalena M. M. Pinto, “Nature-mimetic small molecules: From the land, from the sea, from the lab and through the looking-glas…”, 8th Brazilian Symposium on Medicinal Chemistry, Búzios, Rio de Janeiro, Brazil, November 27- 30, 2016

 

  • Madalena M. M. Pinto, Chiral derivatives of xanthones: bioactive small molecules and analytic tools, 3rd Portuguese Meeting on Medicinal Chemistry, 1st Portuguese- Spanish-Brazilian Meeting on Medicinal Chemistry,28-30 November 2012

– Madalena M. M. Pinto, Ciclo de conferências “A investigação nas ciências farmacêuticas” Ciências Farmacêuticas: ontem, hoje e amanhã, no âmbito das comemorações do Centenário de Aníbal Cunha, Salão nobre complexo ICBAS-FFUP, 27 september de 2012

– Madalena M. M. Pinto, A Química Medicinal e o Ambiente: a (inter)ligação “perfeita ?, 3rd Portuguese Meeting on Medicinal Chemistry, 1st Portuguese- Spanish-Brazilian Meeting on Medicinal Chemistry,28-30 November 2012

– Madalena M. M. Pinto, “At the Cross Roads of Chemistry, Biology, and Nanothecnology”, 3rd Congress of the Portuguese Society of Pharmaceutical Sciences, 9th Portuguese-Spanish Conference on Controlled Drug Delivery, Porto, Portugal, 13-15 October 2011

– Madalena M. M. Pinto “Pequenas moléculas multiativas: estruturas “promíscuas” ou “privilegiadas”, eis a questão!”, no âmbito do CONHECIMENTO NA UP, Porto, 26 Maio 2011

Invited Speaker

– Madalena M. M. Pinto, “Xanthone derivatives: a chemical library of natural mimics for biological diversity”. 6th International Conference on Natural Products for Health and Beuty (NATPRO-6), Khon Kaen, Thailand, 21-23 January, 2016

– Madalena M. M. Pinto, “Chiral derivatives of xanthones: from bioactive small molecules to analytic tools”, Faculty of Sciences, Kasetsart University, Bangkok, Thailand, Portugal, 11 November 2014

– Madalena M. M. Pinto, “Dual anticoagulant/antiplatelet small molecules: overcoming the limitations of antithrombotic therapy”, Faculty of Sciences, Kasetsart University, Bangkok, Thailand, Portugal, 11 November 2014

– Madalena M. M. Pinto, “Multifunctional novel small-molecules to overcome drug resistance in cancer”, no XX Porto Cancer Meeting, Porto, Portugal, 28-29 April, 2011

– Madalena M. M. Pinto, “Xanthone Derivatives: ‘Promiscuous’ or ‘Priviledge’, that’s the question!”, 5th Brazilian Symposium on Medicinal Chemistry (BRAZMEDCHEM), Ouro Preto-MG, Brazil, 6-9 November, 2010

– Madalena M. M. Pinto, “Caminhos Cruzados da Química e Biologia”, in “Conferência: Microbiologia e Biologia do Cancro”, Faculty of Pharmacy, University of Porto, Portugal, 11 de Dcember 2009.

– Madalena M. M. Pinto, “At the crossroads of Chemistry and Biology: hits and leads generation”, Faculty of Science, Kasetsart University, Bangkok, Thailand (28 November 2008).

– Madalena M. M. Pinto, “Classic and Rational Strategies for Bioactive Xanthones”, Department of Pharmacology, Faculty of Medicine, University of Khon Kaen, Khon kaen, Thailand, 17 Janeiro de 2005.

– Madalena M. M. Pinto, “Xantone derivatives in the context of the search for new drugs “- Pos-graduate Course in Science, Education and Inovation, University of Porto (21 October 2003)

– Madalena M. M. Pinto, “The influence of the Organic Chemistry in Medicinal Chemistry”- 23ª Reunião Anual da Sociedade Brasileira de Química “Brasil 500- A Ligação Química Brasil/Portugal”, Poços de Caldas. Minas Gerais, Brasil (23 – 26 May 2000)

– Madalena M. M. Pinto, “Medicinal Chemistry – A via to new drugs” – III Jornadas Internacionais da COFANOR, Fundação Eng. António de Almeida, Porto (21 October 1999)

– Madalena M. M. Pinto, “Heterocycles: Their importance in Medicinal Chemistry” – Department of Chemistry, University of Minho (18 June 1999)

– Madalena M. M. Pinto, “Xanthones and Xanthonolignoids – Synthesis and Biological Activity” – Faculty of Pharmacy, University of Lausanne, Switzerland (11 July 1995)

– Madalena M. M. Pinto, “Non classic Pharmacochemistry: What future? Faculdade de Farmácia da Universidade de Lisboa (24 June 1992).

– Madalena M. M. Pinto, “Supramolecular Chemistry applied to Medicinal Chemistry” Chemistry Department of Nova University of Lisbon, Portugal (4 de Maio de 1992).

– Madalena M. M. Pinto, “Nature: Model for Chemists”- Portuguese Society of Biology, Faculty of Sciences, Porto, Portugal Porto (14 de December de 1984).

Invited Oral Communications

– Emília Sousa, Ana Oliveira, Marta Correia-da-Silva, Vanessa Rodrigues, Raquel T. Lima, M. Helena Vasconcelos, Madalena Pinto, “Curcumin, a valuable model for new cytotoxic agents to circumvent multidrug resistance”, 6th International Conference on Natural Products for Health and Beuty (NATPRO-6), Khon Kaen, Thailand, 21-23 January, 2016

– M. Correia-da-Silva, J. R. Almeida, Isabel Cunha, E. Sousa, M. Pinto, V. Vasconcelos. “Other face of the anticoagulant sulfated molecules coin: the promising of non-toxic antifouling agents”. First International Christmas Caparica Congress in Translational Chemistry IC3TC-2015, Lisbon, Portugal, December 7-10, 2015

– Sousa, E.; Palmeira, A.; Oliveira, A.; Lopes-Rodrigues, V.; Correia-da-Silva, M.; Lima, R. T.; Vasconcelos, M. H.; Pinto, M. M., “Thioxanthones derivatives as dual inhibitors of P-glycoprotein and tumor cell growth”.,  W11-4. 51st Congress of the European Societies of Toxicology – EUROTOX 2015, Porto, Portugal, September-13-16, 2015.

– M. Teixeira, M. Pedro, F. Cerqueira, M. S. J. Nascimento, M. M. M. Pinto and C. M. Barbosa, “Contribution of Nanotechnology to Optimize the Delivery of Xanthone Derivatives”, 1st National Meeting on Medicinal Chemistry, Faculty of Sport Science of the University of Porto, Portugal, 13 – 15 November 2008

– A. F. Palmeira1, A. Paiva, E. Sousa, M. Pinto, H. Seca , G. M. Almeida, R. T. Lima, M. H. Vasconcelos, “XP13 – A Novel Xanthone Derivative with Antiproliferative and Apoptotic Effects in Leukaemia Cell Lines”, 1st National Meeting on Medicinal Chemistry, Faculty of Sport Science of the University of Porto, Portugal, 13 – 15 November 2008

– César Portela, Carlos M. M. Afonso, Madalena M. M. Pinto, Maria João Ramos, “New xanthonic ligands with potential antimalarial activity: Rational design and synthesis”, 6º Encontro Nacional de Química Orgânica, Universidade do Minho, Braga, 20 -22 de July 2005.

– Madalena. M.M. Pinto, “Xanthone Derivatives: an Iberoamerican Chemical Bridge?” Reunião de Coordenação do Subprograma X, Química Fina Farmacêutica, Workshop: “Novas aproximações para descoberta de fármacos. Possibilidades e limitações na América Latina”, Rio de Janeiro (Brasil), 19-24 August 2001.

– M.M.M. Pinto, M.E. Sousa, C. Afonso, A. Silva, O. R. Gottlieb, M. S. J. Nascimento, M. Pedro, F. Cerqueira, “Natural Kielcorins as a Model for Design and Synthesis of Novel Bioactive Compounds”, IUPAC 22th International Symposium on the Chemistry of Natural Products, São Carlos, Brazil, 4-8 September, 2000.

– Madalena M. M. Pinto, “The Colors of the Health in the Plant Kingdom”, XVI Encontro Nacional da Sociedade Portuguesa de Química, Guimarães, 22 – 25 de September, 1998.

– Madalena M. M. Pinto, “Molecular Clefts in Molecular Recognition of Antiviral Agents”, XV Encontro Nacional da Sociedade Portuguesa de Química, Porto, 22 – 25 May, 1996.

– Madalena M. M. Pinto, “Bioactivity of Xanthones and Derivatives – The involvement of Free Radials” – 2º Congresso de Radicais Livres em Química, Biologia e Medicina, Faculdade de Ciências do Porto, 23 -25 de October, 1995.

– Madalena M. M. Pinto, “Natural Products: Molecular Diversity versus Bioactivity ” 14º Encontro Anual da Sociedade Portuguesa de Química, Universidade de Aveiro, 5 a 8 de April, 1994.

– Madalena M. M. Pinto, “Supramolecular Chemistry applied to Pharmacochemistry” ” 13º Encontro Anual da Sociedade Portuguesa de Química, Instituto Superior Técnico, 29 January a 1 February, 1992.

Oral Communications (last 5 years)

– Oral Communications in National Conferences:

– C. Fernandes, M.E. Tiritana, M.M.M. Pinto, New brush-type chiral stationary phases based on xanthone derivatives for liquid chromatography, 10º Encontro Nacional de Cromatografia, Bragança, 4-6 December, 2017.

 

– Vilas-Boas, C.; Cravo, S.; Sousa, E.; Pinto, M.; Correia-da-Silva, M. Seawater degradation studies of gallic acid persulfate, a promising synthetic antifouling agent. 10º Encontro Nacional de Cromatografia (10ENC), Bragança, Portugal, December 04-06, 2017.

– A. Reis-Mendes, S. Gomes, R. Carvalho, F. Carvalho, F. Remião, M. Pinto, M. L. Bastos, E. Sousa, V. M. Costa. Mitoxantrone and its naphthoquinoxaline metabolite: a comparative study in differentiated h9c2 cells. XLVII Reunião Anual da Sociedade Portuguesa de Farmacologia XXVI Reunião De Farmacologia Clínica XVII Reunião De Toxicologia, Coimbra, Portugal, 2 a4 de fevereiro de 2017, C122.

– B. Freitas, C. Fernandes, M.E. Tiritan, A.M.S. Silva, M.M.M. Pinto, Strategy for synthesis of chiral derivatives of xanthones in enantiomerically pure form, IJUP 2017, 10th Meeting of Young Researches of University of Porto, 8-10 February, 2017.

– A. Lopes, E. Martins, R. Silva, C. Fernandes, A. Palmeira, F. Remião, M.M.M. Pinto, E. Sousa, Small Chiral Molecules as potential P-gp Modulators: Synthesis and Studies of Enantioselectivity, IJUP 2017, 10th Meeting of Young Researches of University of Porto, 8-10 February, 2017.

– P. Pinto, P.M.A. Silva, S. Marques, J. Costa, J. Moreira, A. Palmeira, M. Pinto, J. Salvador, H. Bousbaa, H. Cidade, “Synthesis of Bioactive Chalcones and Their Heterocyclic Derivatives as Potential Antitumor Agents” IJUP 2017 -10th Meeting of Young Researches of U. Porto, Porto, Portugal, 8-10 February, 2017.

– M.I.S. Cruz, S.M. Cravo, H. Cidade, M. Pinto, “Synthesis and Biological Evaluation of Xanthone and Flavone Derivatives as Potential Dual Agenst to Combat Alzheimer’s Diasease”, IJUP 2016 -9th Meeting of Young Researches of U. Porto, Porto, Portugal, 17-19 February, 2016 (10896).

– J. Moreira, S. Salazar, M. Pinto, M. Leão, M. Pinto, L. Saraiva, H. Cidade, “Flavonoid derivatives with caspase modulatory activity” IJUP 2016 – 9th Meeting of Young Researches of U. Porto, Portugal, 17-19 February, 2016 (10868).

– Raimundo, L.; Gomes, S.; Leão, M.; Soares, J.; Ramos, H.; Bessa, C.; Pinto, M.; Inga, A.; Cidade, H.; Saraiva, L. Enhanced cytotoxicity against human tumor cells using prenylated chalcones through disruption of the p53-MDM2 interaction. XXII Encontro Luso-Galego de Química, November 9-11, 2016 (O58, pag. 216).

– Oral Communications in International Conferences:

– E. Sousa, S. Long, P. Boonpothong, D. Resende, F. Durães, A. Palmeira, A. M. S. Silva, A. Kijjoa, M. Pinto. Models from the sea: synthesis of potential new antibacterial agents. 2nd International Christmas Caparica Congress in Translational Chemistry – IC3TC-2017, Lisboa, Portugal, 4 a 7 de dezembro de 2017.

– Correia-da-Silva, M., Sousa, E., Almeida, J. R., Cunha, I., Vasconcelos, V., Pinto, M. Synthesis and Environmental Fate Evaluation of New Nature-Inspired Antifouling Compounds. OP Env Safe #3. 18th European Meeting on Environmental Chemistry (EMEC18), Porto, Portugal, November 26-29, 2017.

– E. Sousa, S. Long, P. Boonpothong, D. Resende, A. M. S. Silva, A. Kijjoa, M. Pinto. Marine-fungi natural products as models for new antibacterial agents. IL5. Transmediterranean Colloquium on Heterocyclic Chemistry (TRAMECH IX 2017), Fez, Morrocos, 22 -25 November 2017.

– I. Hrynchak, A. Reis-Mendes, A. Palmeira , M. L. Bastos, M. Pinto, V. Costa, E. Sousa. Old Pharmaceuticals with New Applications: the Case Studies of Lucanthone and Mitoxantrone. 3rd International Electronic Conference on Medicinal Chemistry, 1 -30 November 2017; (video key lecture).

– M. Correia-da-Silva, E. Sousa, J. R. Almeida, I. Cunha, V. Vasconcelos, M. Pinto. Synthesis and Environmental Fate Evaluation of New Nature-Inspired Antifouling Compounds. 18th European Meeting on Environmental Chemistry (EMEC18), Porto, Portugal, 26 -29 November 2017.

– M. Correia-da-Silva, E. Sousa, M. Pinto. One decade of synthesis of sulfated small molecules: from pharmaceutical to environmental applications. SUPA 2017 Conference, Birmingham, Reino Unido, 23 -25 April 2017

 Electronic Communications – Internationals:

– Neves, A.; Correia-da-Silva, M.; Silva, P.; Ribeiro, D.; Sousa, E.; Bousbaa, H.; Pinto, M. Synthesis and Tumor Cell Growth Inhibitory Effects of New Flavonosides and Xanthonosides. 3rd International Electronic Conference on Medicinal Chemistry, November 1–30, 2017.

– W.W.M. Zin, C. Prompanya, C. Fernandes, S. Cravo, M.M.M. Pinto, A.Kijjoa, Chiral Liquid Chromatography in analysis of the stereochemistry of marine natural compounds: contribution for Medicinal Chemistry, 3rd International Electronic Conference on Medicinal Chemistry, November 1-30, 2017.

– A. R. Neves, M. Correia-da-Silva, P. M. A. Silva, D. Ribeiro, E. Sousa, H. Bousbaa, M. Pinto. Synthesis and Tumor Cell Growth Inhibitory Effects of New Flavonosides and Xanthonosides. 3st International Electronic Conference on Medicinal Chemistry, 1 a 30 de novembro de 2017

– A. Oliveira, V. Rodrigues, E. Sousa, M. H. Vasconcelos, M. Pinto, E. Sousa. “Curcumin derivatives as potential P-glycoprotein inhibitors: synthesis and stability studies”. 9º Meeting of Young Researchers of University of Porto (IJUP16), Porto, Portugal, 17-19 February, 2016.

– A. Lemos, A. S. Gomes, A. Palmeira, L. Saraiva, M. Pinto, E.Sousa.” Aminated derivatives for cancer therapy: Targeting p53 -MDM2 interaction with LEM2″. 9º Meeting of Young Researchers of University of Porto (IJUP16), Porto, Portugal, 17-19 February, 2016.

– Neves, A. R.; Sousa, E.; Pinto, M.; Correia-da-Silva, M. “Playing with hydrophilic and hydrophobic balance of bioactive sulfated compounds”. 9º Meeting of Young Researchers of University of Porto (IJUP16), Porto, Portugal, 17-19 February, 2016.

– Carvalho, C.; Duarte, B.; Marques, F.; Pinto, M.; Sousa, E.; Correia-da-Silva, M. “New triazole and non-triazole linked coumarin glucosides: synthesis, structure elucidation and biological activity”. 9º Meeting of Young Researchers of University of Porto (IJUP16), Porto, Portugal, 17-19 February, 2016. 42.

– Correia-da-Silva, M.; Almeida, J. R.; Cunha, I.; Sousa, E.; Pinto, M.; Vasconcelos, V. “Other face of the anticoagulant sulfated molecules coin: the promising of non-toxic antifouling agents”. First International Christmas Caparica Congress in Translational Chemistry – IC3TC-2015, Lisboa, Portugal,7-10 December 2015

– Raquel T. Lima, Diana Sousa, Ana Sara Gomes, Nuno Mendes, Rune Matthiesen, Madalena Pedro, Madalena M. Pinto, Emília Sousa, M. Helena Vasconcelos, “Antitumor activity of TXA1, an autophagy inducer which affects cholesterol localization”, 11 Encontro Nacional de Química Orgânica e 4 Encontro Nacional de Química Terapêutica, 1-3 December 2105, Porto, Portugal, MC-1pp 61

– J. Soares , R. Vieira, J. Neves, S. Reis, M. Pinto, C Azevedo, Carlos Afonso, “Lessons from the study of the binding mechanism of “hit” compounds to albumin: fluorescence and in silico experiments applied to xanthone derivatives”, 11 Encontro Nacional de Química Orgânica e 4 Encontro Nacional de Química Terapêutica, 1-3 December 2015, Porto, Portugal, MC-20, pp. 80

– Neves, A. R.; Sousa, E.; Pinto, M.; Correia-da-Silva, M.” Potential Orally-Active Heparin-Like Compounds: Synthesis and Anticoagulant Activity”. 1st International Electronic Conference on Medicinal Chemistry, 2-27 November 2015

– A. Lemos, A. S. Gomes, A. Palmeira, L. Saraiva, M. Pinto, E. Sousa. “Xantonas como fonte de inspiração para a obtenção de novos inibidores da interação p53/p73:MDM2”. 1º Encontro Científico do Núcleo de Estudantes de Química da Associação Académica de Coimbra, Coimbra, Portugal, 19-20 November 2015

– Sousa, E., Palmeira, A., Oliveira, A., Lopes-Rodrigues, V., Correia-da-Silva, M., Lima, R. T., Vasconcelos, M. H., Pinto, M. M., “Thioxanthones derivatives as dual inhibitors of P-glycoprotein and tumor cell growth”. W11-4. 51st Congress of the European Societies of Toxicology – EUROTOX 2015, Porto, Portugal, September 13-16, 2015.

– A. Lemos, P. Puthongking, A. Palmeira, A. Kijjoa, L. Saraiva, M. Pinto, E. Sousa. “Xanthone as a promising scaffold to develop new potential inhibitors of p53:MDM2 interaction”. IJUP’15 – 8º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 13-15 May 2015.

– A. Oliveira, E. Sousa, M. H. Vasconcelos, M. Pinto. “Synthesis of curcumin derivatives with potential to inhibit P-glycoprotein expression”. 8th edition IJUP – Meeting of Young Researchers of University of Porto, Porto, Portugal, 13-15 May 2015, A3, page 105.

– A. Lemos, P. Brandão, A. Palmeira, M. Pinto, L. Saraiva, E. Sousa. “A hybridization approach to obtain new xanthone derivatives as potential inhibitors of p53:MDM2 interaction”, III Encontro Nacional de Estudantes de Qumíca, Aveiro, Portugal, 27-29 March 2015

– A Gomes, Leão, M., Soares, J., Raimundo, R., Ramos H., Bessa C., Queiroz, G., Domingos, S., Palmeira A., Sousa, E., Pinto, M., Inga, A., Cidade, H., Saraiva, L. “A new inhibitor of the p53-MDM2 interaction derived from naturally occurring chalcones”. XLV Reunião Anual da Sociedade Portuguesa de Farmacologia, Lisboa, Portugal, 5-6 February 2015., S12C78.

– Renata Silva, Andreia Palmeira, Helena Carmo, Daniel Barbosa, Mariline Gameiro, Ana Gomes, Ana Mafalda Paiva, Sara Gomes, Emília Sousa, Madalena Pinto, Maria de Lourdes Bastos, Fernando Remião. “P-glycoprotein induction and activation by newly synthetized (thio)xanthones: in vitro and in silico studies”. XLV Reunião Anual da Sociedade Portuguesa de Farmacologia, Lisboa, Portugal, 5-6 February 2015.

– R. Silva, M. Gameiro, E. Sousa, H. Carmo, A. M. Paiva, A. Palmeira, D. Barbosa, M. Pinto, M. L. Bastos, F. Remião. “New thioxanthones and dihydroxylated xanthones as P-glycoprotein inducers/activators”. XLIV Reunião Anual da Sociedade Portuguesa de Farmacologia, Coimbra, Portugal, 5-7 February 2013, S11C1, 143.

– C. Pereira, I. Coutinho, V. Lopes-Rodrigues, M.P. Neves, R.T. Lima, A. Kijjoa, M. Pinto, H. Cidade, M.H.Vasconcelos, L. Saraiva.” Small-molecule activators of caspase-7 with potential antitumor activity identified using a yeast assay”. XLIII Reunião Anual da Sociedade Portuguesa de Farmacologia, XXXI Reunião de Farmacologia Clínica, XII Reunião de Toxicologia, Auditório ICBAS-FFUP, Porto, Portugal, 6-8 February 2013.

– Patrão, M.; Correia-da-Silva, M.; Pinto, M. M. M.; Sousa, E. “Synthesis of conjugates of polysulfated diosmin as potential orally-active anticoagulant agents”. OC. iMed – Innovating Medicine Conference, Lisbon, Portugal,October 12, 2013.

– J. Soares, C. Azevedo, A. Palmeira, D. Sousa, R. Lima, M. Pedro, M. Vasconcelos, C. Afonso, S. Reis, M.Pinto, “Multidimensional optimization of pyranoxanthones with potential antitumor activity”, 10ENQO-1SLB,Faculty of Pharmacy, University of Lisbon, Lisbon, Portugal, 04-06 September 2013.

– R.T. Lima, D. Sousa, H. Seca, A. Palmeira, A. M. Paiva, A. S. Gomes, V. Lopes-Rodrigues, J.E. Guimarães, M.X. Fernandes, M. Pedro, F. Cerqueira, M.M. Pinto, E. Sousa, M.H. Vasconcelos. “A new small molecule with antitumour and chemosensitizing potential as P-gp inhibitor”. COST Action CM1106 “Chemical Approaches to Targeting Drug Resistance in Cancer Stem Cells”, IPATIMUP, Porto, Portugal, 21-22 February 2013.

– N. Machado, M. Leão, A. Paiva, A. Palmeira, C. Pereira, L. Saraiva, M. Pinto, E. Sousa. “Virtual screening of a focused library of cell growth inhibitors to identify potential inhibitors of p53:MDM2 interaction”. IJUP’13 – 6º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 13-15 February 2013.

– J. Almeida, R. Castanheiro, J. Soares, C. Azevedo, C. Afonso, S. Reis, M. Pinto, “Evaluation of physicochemical properties of synthetic prenylated xanthone derivatives”, IJUP’13 – 6º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 13-15 February 2013.

– R. Vieira, D. Marques, J. Soares, C. Azevedo, A. Palmeira, Carlos M. M. Afonso, M. S. Reis, M. M. Pinto, “Binding mechanism of new potential antitumor molecules to albumin: a fluorescence and computational study applied to xanthone derivatives”, IJUP’13 – 6º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 13-15 February 2013.

Poster Communications (last 5 years)

433 – S. Long, N. Thongdee, J.B. Loureiro, M.M. Pinto, P. Puthongking, L. Saraiva, E. Sousa. Aminocarbazole alkaloid derivatives as potential modulators of p53mutants, 18th International Conference on MedicinalChemistry & Targeted Drug Delivery, Dallas, USA, 6-8 December, 2017.

432 – Correia-da-Silva, M., Almeida, J. R., Pereira, D., Moreira, J., Vasconcelos, V., Pinto, M., Cidade, H. Synthesis of Chalcone Derivatives and Anti-settlement Activity Against Mytilus galloprovincialis Larvae. PP Env Safe #6. 18th European Meeting on Environmental Chemistry (EMEC18), Porto, Portugal, November 26-29, 2017.

431 – Neves, A. R., Almeida, J. R., Antunes, J., Vasconcelos, V., Sousa, E., Pinto, M., Correia-da-Silva, M. Synthesis of Steroid Derivatives with Anti-microfouling and Anti-macrofouling Properties. PP Env Safe #16. 18th European Meeting on Environmental Chemistry (EMEC18), Porto, Portugal, November 26-29, 2017.

430 – Y.Z. Phyo, C. Fernandes, M.E. Tiritan, S. Cravo, A.M.S. Silva, A. Kijjoa, M.M.M. Pinto, Analytical applications of xanthone derivatives as chiral selectors for liquid chromatography, Transmediterranean Colloquium on Heterocyclic Chemistry (TRAMECH IX 2017), Fez, Morocco, 22-25 November, 2017.

429- N. Lopes, S. Long D. Resende A. Kijjoa A. Silva A. Pina, T. Fernández-Marcelo, M. H. Vasconcelos, M. Pinto, E. Sousa. Synthesis and tumor cell growth inhibitory effects of the marine product analogues of fiscalin B, 12th Young European Scientist Meeting (YES2017), Porto, Portugal, 14 -17 de September 2017.

428 – I. Hrynchak, E. Sousa, M. L. Bastos, M. Pinto, and V. M. Costa. Studies towards the synthesis of dicarboxylic acid metabolite of mitoxantrone. 12th Young European Scientist Meeting (YES2017), Porto, Portugal, 14 -17 de September 2017.

427- D. I. S. P. Resende, S. Long, P. Boonpothong, A. M. S. Silva, A. Kijjoa, E. Sousa, M. M. M. Pinto. Synthetic strategies for the synthesis of quinazoline alkaloid derivatives with promising biological activities. 20th European Symposium on Organic Chemistry (ESOC 2017), Cologne, Germany, 2 – 6 July 2017 (LM002).

426 – C. Fernandes, M.L. Carraro, M.E. Tiritan, S. Marques, P.M.A. Silva, H. Bousbaa, A.M.S. Silva, M. Pinto, Synthesis, enantiomeric purity evaluation and enantioselectivity study on human tumor cell lines of new chiral derivatives of xanthones, EFMC-ASMC’17-VII – International Symposium on Advances in Synthetic and Medicinal Chemistry, Vienna, Austria, 27-31 August 2017.

425 – H. Cidade, P. Brandão, S. Carvalho, J. Moreira, D. Pereira, S. Cravo, J. Soares, L. Saraiva, M. Pinto, “Potential inhibitors of the p53-MDM2 interaction: synthesis and biological evaluation”, EFMC-ASMC17-VII International Symposium on Advances in Synthetic and Medicinal Chemistry, Vienna, Austria, 27-31 August 2017

Nationals

424- J. Ribeiro, C. Fernandes, M.E. Tiritan, A.M.S. Silva, M.M.M. Pinto, Preparation of a new chiral stationary phase for liquid chromatography based on a small molecule, 10º Encontro Nacional de Cromatografia, Bragança, 4-6 December, 2017.

423- J.P. Carmo, C. Fernandes, M.E. Tiritan, C. Afonso, M.M.M. Pinto, Liquid chromatography enantioseparation of xanthone derivatives on a human serum albumin stationary phase, 10º Encontro Nacional de Cromatografia, Bragança, 4-6 December, 2017.

422- Y.Z. Phyo, A. Palmeira, S. Cravo, M.E. Tiritan, A.Kijjoa, M.M.M. Pinto, C. Fernandes, Enantiomeric separation and chiral recognition mechanisms of different macrocyclic glycopeptide-based chiral stationary phases, 10º Encontro Nacional de Cromatografia, Bragança, 4-6 December, 2017.

421- C. Vilas-Boas, S. Cravo, E. Sousa, M. Pinto, M. Correia-da-Silva. Development and validation of an HPLC method for quantification of the biocide Econea®. 10º Encontro Nacional de Cromatografia (10ENC), Bragança, Portugal, 4 – 6 December 2017.

420- S. Long, D. Resende, A. Kijjoa, A. M. S. Silva, A. Pina, T. Fernández-Marcelo, M. H. Vasconcelos, E. Sousa, M. Pinto. Antitumor Activity of Quinazolione Alkaloids-Inspired in Marine Products. XXV Encontro Nacional Sociedade Portuguesa de Química, Lisboa, Portugal, 16 – 19  July 2017.

419- P. Boonpothong, D. Resende, A. Kijjoa, E. Sousa, M. Pinto, Progress towards neofiscalin A synthesis, a potent antibacterial agent, XXV Encontro Nacional Sociedade Portuguesa de Química, Lisboa, Portugal, 16 – 19  July 2017.

418- A. Reis-Mendes, S. Gomes, R. Carvalho, F. Carvalho, F. Remião, M. Pinto, M. L. Bastos, E. Sousa, V. M. Costa. Mitoxantrone and its naphthoquinoxaline metabolite: a comparative study in differentiated h9c2 cells. SPF 2016 – XLVII Reunião Anual Da Sociedade Portuguesa De Farmacologia, XXXV Reunião De Farmacologia Clínica, XVI Reunião de Toxicologia, Coimbra, Portugal, 2- 4 February 2017

417- Coutinho Alves, A.D.; Sousa, E.; Pinto, M.M.M.; Correia da Silva, M.; Ferreira, D.; Costa, P. Development of an HPLC method for the quantification of a new glycosylated xanthone with cell growth inhibitory activity. 10th Meeting of Young Researchers of University of Porto (IJUP17), Porto, Portugal, 8- 10 February 2017

416- Carvalhal, F.; Sousa, E.; Neves, A. R.; Correia-da-Silva, M.; Pinto, M. Synthesis and structural elucidation of 3,4-dihydroxyxanthone derivatives. 10th Meeting of Young Researchers of University of Porto (IJUP17), Porto, Portugal, 8- 10 February 2017

415- Vilas-Boas, C.; Cravo, S.; Sousa, E.; Pinto, M.; Correia-da-Silva, M. Sea-water solubility and degradation studies of sulfated small molecules. 10th Meeting of Young Researchers of University of Porto (IJUP17), Porto, Portugal, 8- 10 February 2017

414- Martins, B. T.;Pereira, D.; Correia-da-Silva, M.; Cidade, H.; Pinto, M. Synthesis of potential bioactive flavone derivatives. 10th Meeting of Young Researchers of University of Porto (IJUP17), Porto, Portugal, 8- 10 February 2017.

413- Confraria, C.; Almeida, I. F.; Pinto, M.; Sousa, E.; Correia-da-Silva, M. Synthesis of a Water Soluble Resveratrol Derivative for Skin Care Formulations. 10th Meeting of Young Researchers of University of Porto (IJUP17), Porto, Portugal, 8- 10 February 2017

412- I. Hrynchak, E. Sousa, M. L. Bastos, M. Pinto, V. M. Costa. Synthesis and characterization of the main metabolites of mitoxantrone. 10º Meeting of Young Researchers of University of Porto (IJUP17), Porto, Portugal, 8- 10 February 2017

411- P. Boonpothong, D. Resende, A. Kijjoa, E. Sousa, M. Pinto. Synthetic Studies Towards Neofiscalin A, a Potent Antibacterial Agent. 10º Meeting of Young Researchers of University of Porto (IJUP17), Porto, Portugal8- 10 February 2017

410- N. Lopes, S. Long, D. Resende, A. Kijjoa, A. Silva, M. Pinto, E. Sousa. Synthetic strategies for fiscalin B and analogues. 10º Meeting of Young Researchers of University of Porto (IJUP17), Porto, Portugal, 8- 10 February 2017

409- A. Reis-Mendes, S. Gomes, R. Carvalho, F. Carvalho, F. Remião, M. Pinto, M. L. Bastos, E. Sousa, V. M. Costa. Mitoxantrone and its naphthoquinoxaline metabolite: a comparative study in differentiated h9c2 cells. SPF 2016 – XLVII Reunião Anual Da Sociedade Portuguesa De Farmacologia, XXXV Reunião De Farmacologia Clínica, XVI Reunião de Toxicologia, Coimbra, Portugal, 2 – 4 February 2017.

408- C. Leite, C. Fernandes, M.E. Tiritan, M. Pinto, Total synthesis and structure elucidation of 3-carboxymethoxyxanthone, IJUP 2017, 10th Meeting of Young Researches of University of Porto, Encontro de Investigação Jovem da Universidade do Porto,  8-10 February, 2017.

407- J. Ribeiro, C. Fernandes, M.E. Tiritan, M.M.M. Pinto, Synthesis and structure elucidation of carboxyxanthone derivative, IJUP 2017, 10th Meeting of Young Researches of University of Porto, 8-10 February, 2017.

406- H. Ribeiro, V. Barbosa, A.S. Malheiro, S. Dias, M.E. Tiritan, A.M.S. Silva, C. Fernandes, M.M.M. Pinto, Strategy for synthesis of enantiomerically pure xanthones – amino acid derivatives, IJUP 2017, 10th Meeting of Young Researches of University of Porto, 8-10 February, 2017.

405 – C. M. Machado, J. Moreira, A. Bartzoka, H. Cidade, M. Pinto, “Chalcone Isosteres: Synthesis and Structure Elucidation”, IJUP 2017 -10th Meeting of Young Researchs of U. Porto, Porto, Portugal, 8-10 February, 2017.

404 – Almeida, J. R.; Correia-da-Silva, M.; Sousa, E.; Pinto, M.; Vasconcelos, V.; Cunha, I. Antifouling properties of nature-inspired synthetic compounds. International Congress on Marine Corrosion and Fouling 18th ICMCF, Toulon, France, June 19-24, 2016.

403 –  A. Lopes, R. Silva, C. Fernandes, F. Remião, M. Pinto, E. Sousa. Chiral Thioxanthones as Promising P glycoprotein Modulators. 5th Portuguese Young Chemists Meeting and 1st European Young Chemists Meeting, Guimarães, Portugal. 26-29 April 2016

402 – A. Lopes, S. Long, C. Fernandes, M. Pinto, E. Sousa. Synthesis of new tioxanthone derivatives. 9th Meeting of Young Researches of University of Porto, Porto, Portugal. 17-19 February 2016.

401- Câmara, A.; Neves, A. R.; Pinto, M.; Sousa, E.; Correia-da-Silva, M. Synthesis of a natural marine antifouling compound. 9º Meeting of Young Researchers of University of Porto (IJUP16), Porto, Portugal, 17-19 February, 2016.

400 –  Gatarz, S.; Neves, A. R.; Sousa, E.; Pinto, M.; Correia-da-Silva, M. Scale-up synthesis of promising antifouling compounds. 9º Meeting of Young Researchers of University of Porto (IJUP16), Porto, Portugal, 17-19 February, 2016.

379- C. Fernandes, A. Santos, J. Soares, S. Cravo, M.E. Tiritan, C. Afonso, M. Pinto ,An example of the key role of HPLC in Medicinal Chemistry: determination of lipophilicity of a xanthone derivatives library, 11 Encontro Nacional de Química Orgânica e 4 Encontro Nacional de Química Terapêutica, 1-3 December 2105, Porto, Portugal, P-10, pag 100

378 – E. Sousa, A. Lemos, A. S. Gomes, A. Palmeira,L. Saraiva,M. Pinto, Xanthone as a valuable scaffold to identify new promising antitumor agents via inhibition of p53/p73:MDM2 interaction, 11 Encontro Nacional de Química Orgânica e 4 Encontro Nacional de Química Terapêutica, 1-3 December 2105, Porto, Portugal, P-14, pag. 104

377 – Cidade H, Pereira D, Lima RT, Palmeira A, Seca H, Soares J, Gomes, Raimundo L, Maciel C, Sousa E, Vasconcelos MH, Saraiva L, Pinto M, Promising Chalcone Derivatives as New Inhibitors of p53-MDM2 Interaction, 11 Encontro Nacional de Química Orgânica e 4 Encontro Nacional de Química Terapêutica, 1-3 December 2105, Porto, Portugal, P-16, pag. 104

376 – Cruz, M. I. S., Cravo, S. M., Cidade, H. and Pinto, M, Xanthone and Flavone Derivatives as Potential Dual Agents for Alzheimer’s Disease, 11 Encontro Nacional de Química Orgânica e 4 Encontro Nacional de Química Terapêutica, 1-3 December 2105, Porto, Portugal, P-17, pag 107

375 – Marta Correia da Silva, Catarina Carvalho, Emília Sousa, Madalena Pinto, Synthesis of Innovative Anticoagulant Hybrids, 11 Encontro Nacional de Química Orgânica e 4 Encontro Nacional de Química Terapêutica, 1-3 December 2105, Porto, Portugal, P-26, pag. 116

374 – Vanessa Lopes-Rodrigues, Ana Oliveira, Marta Correia-da-Silva, Madalena Pinto, Raquel T.Li­ma, Emília Sousa, M. Helena Vasconcelos, A new curcumin derivative with more potent antitumor and anti-P-glycoprotein activity than curcumin, 11 Encontro Nacional de Química Orgânica e 4 Encontro Nacional de Química Terapêutica, 1-3 December 2105, Porto, Portugal, P-62, pP. 152

373- Neves, A. R.; Correia-da-Silva, M.; Sousa, E.; Pinto, M. Heparin-like small-molecules: reaching oral bioavailability. P28. EFMC Young Medicinal Chemist Symposium, Antwerp, Belgium, 17 September, 2015.

372 – M.L. Carraro, A.S. Silva, C. Fernandes, M.E. Tiritan, A.M.S. Silva and M. Pinto, “Promising new antitumor chiral derivatives of xanthones: synthesis and evaluation of enantiomeric purity by HPLC”, YES METTING, Young European Scientist Meeting, Porto, Portugal, 17-20 September 2015.

371- M.L. Carraro, A.S. Silva, C. Veloso, M.E. Tiritan, A.M.S. Silva, M. Pinto and C. Fernandes, “Promising bioactive chiral derivatives of xanthones using carboxyxanthones as chemical substracts”, II Simposio de Jóvens Investigadores de la Sociedad Española de Química Terapéutica, Madrid, Spain, 12 June 2015.

370 – C. Fernandes, L. Carraro, A. S. Silva, C. Veloso, M. E. Tiritan, A. M. S. Silva, M. Pinto, “New bioactive chiral derivatives of xanthones: synthesis and optimization of their xanthonic building block”, 7th Spanish-Portuguese-Japanese Organic Chemistry Symposium, Seville, Spain, 23-26 de June 2015.

369 – A. Santos, M.E. Tiritan, S. Cravo, M. Pinto and C. Fernandes, “RP-HPLC evaluation of the lipophilicity of chiral derivatives of xanthones: correlation between chromatographic and theoretical methods”, HPLC 2015, Geneva, Switzerland, 21-25 June 2015.

368 – Rocha, V., Marques, C., Contente, S., Sousa, M.E., Palmeira, A., Correia-da-Silva, M., Pinto, M., Sousa Lobo, J.M., Almeida, I.F. Novel resveratrol derivative for skin care. V Congresso Nacional de Ciências Dermatocosméticas, Porto, Portugal, 15 May, 2015.

367 – A. Lemos, P. Puthongking, A. Palmeira, A. Kijjoa, L. Saraiva, M. Pinto, E. Sousa. “Xanthone as a promising scaffold to develop new potential inhibitors of p53:MDM2 interaction”. IJUP’15 – 8º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 13-15 de Maio de 2015.

366 – A. Oliveira, E. Sousa, M. H. Vasconcelos, M. Pinto. Synthesis of curcumin derivatives with potential to inhibit P-glycoprotein expression. 8th edition IJUP – Meeting of Young Researchers of University of Porto, Porto, Portugal, 13-15 May 2015, A3, page 105.

365 – Ana R. Moreira, Gabriela Moreira, Agostinho Lemos, Emília Sousa,, Madalena M. M. Pinto, Paulo Costa, Domingos Ferreira. Synthesis of a xanthonic compound with antitumor activity and development of proliposomes as its delivery system.8º Encontro de Jovens Investigadores da Universidade do Porto (IJUP15), Porto, Portugal, 13-15 maio, 2015.

364 – A. Reis-Mendes, A.S. Gomes, R.A. Carvalho, F. Remião, F. Carvalho, M. Pinto, M.L. Bastos, E. Sousa, and V.M. Costa. The cardiotoxicity of mitoxantrone: A comparative in vitro study between mitoxantrone and its naphthoquinoxaline metabolite. 8º Encontro de Jovens Investigadores da Universidade do Porto (IJUP15), Porto, Portugal, 13-15 maio, 2015.

363 – H. Ramos, S. Gomes, M. Leão, J. Soares, L. Raimundo, G. Queiroz, P. Brandão, M. Pinto, E. Sousa and L. Saraiva. LEM2: a new small molecule inhibitor of the p73-MDM2 interaction. 8º Encontro de Jovens Investigadores da Universidade do Porto (IJUP15), Porto, Portugal, 13-15 maio, 2015.

362 – I. Nogueira, A. Oliveira, P. Melo, F. Ferreira, M. Pinto, E. Sousa. Synthetic and natural dyes as models for bioactive compounds. 8thedition IJUP – Meeting of Young Researchers of University of Porto, Porto, Portugal, 13-15 May 2015, Poster Session, page 278.

361- Moreira, J.; Castro, M.; Fernandes, C.; Correia da Silva, M.; Sousa, E.; Cidade, H.M.; Afonso, C. M.; Pinto, M.; Vasconcelos, V.; Urbatzka R. Plant-derived and synthetic compounds affect the proliferation and metabolic activity of 3T3-L1 preadipocytes. IJUP 2015 – 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 13-15 May 2015.

360 – Carvalho, C.; Correia-da-Silva, M.; Duarte, B.; Marques, F.; Sousa, E.; Pinto, M. Sulfated coumarin glucosides: synthesis and anticoagulant activity. IJUP 2015 – 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 13-15 May 2015.

359 – Neves, A. R.; Correia-da-Silva, M.; Sousa, E.; Pinto, M. Synthesis of a sulfated flavonoid – deoxycholic acid conjugate as a potential orally-active antithrombotic agent. IJUP 2015 – 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 13-15 May 2015.

358 – Zovinec, M.; Neves, A. R.; Correia-da-Silva, M.; Sousa, E.; Pinto, M. Carboxymethylation of flavonoids: synthesis, purification and structure elucidation. IJUP 2015 – 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 13-15 May 2015.

357 – Guerra, A.C.; Correia-da-Silva, M.; Rachão, A.; Veiga, H.; Neves, C.; Sousa, E.; Pinto, M.M.M.; Soares, R.; Negrão, R. Effects on Endothelial Cells and Angiogenesis of Structurally-Diverse Xanthones. IJUP 2015 – 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 13-15 May 2015.

356 -.A.S. Silva, M.E. Tiritan, A.M.S. Silva, M. Pinto and C. Fernandes, “Synthesis of promising bioactive chiral derivatives of xanthones with two stereogenic centres”, IJUP 2015 – 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 13-15 May 2015.

355 – C. Veloso, M. E. Tiritan, A.M.S. Silva, M. Pinto and C. Fernandes, “Synthesis and structural elucidation of a new carboxyxanthone”, IJUP 2015 – 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 13-15 May 2015.

354 – M.L. Carraro, M.E. Tiritan, A.M.S. Silva, M. Pinto and C. Fernandes, “Total synthesis of fluorinated chiral derivatives of xanthones”, IJUP 2015 – 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 13-15 May 2015.

353 – J. Moreira, M. Castro, C. Fernandes, M. Correia da Silva, E. Sousa, H.M. Cidade, C. M. Afonso,M. Pinto, V. Vasconcelos and R. Urbatzka, “Plant-derived and synthetic compounds affect the proliferation and metabolic activity of 3T3-L1 preadipocytes”, IJUP 2015 – 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 13-15 May 2015.

352 – B. Silva, C. Fernandes, M. Pinto, P. Guedes de Pinho and F. Remião, “Chiral HPLC enantioresolution of synthetic cathinones “Legal Highs”, IJUP 2015 – 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 13-15 May 2015.

351- A. Santos, S. Cravo, M.E. Tiritan, M. Pinto and C. Fernandes. Estimating the lipophilicity of chiral derivatives of xanthones by RP-HPTLC. IJUP 2015 – 8th Meeting of Young Researchers of U. Porto, Porto, Portugal, 13-15 May 2015.

350 – Rocha, V, Marques, C, Sousa, ME, Cidade, H, Pinto, M, Sousa Lobo, JM, Almeida, IF, Study of the potential for topical application of a new antioxidant xanthone, V Congresso Nacional de Ciências Dermatocosméticas, Porto, Portugal, 15 May, 2015.

349 – Neves, A.R.; Correia-da-Silva, M.; Sousa, E.; Duarte, P.; Silva, P; Bousbaaa, H.; Pinto, M. Acetylated flavonoids and xanthones: synthesis and screening for antitumor activity. III Encontro Nacional de Estudantes de Química, Aveiro, Portugal, 27-29 March, 2015.

348 – A. Oliveira, E. Sousa,  M. H. Vasconcelos, M. Pinto. ” Curcumin, a valuable model for novel therapeutic agents: synthesis and biological activities of curcumin derivatives “, III Encontro Nacional de Estudantes de Qumíca, Aveiro, Portugal, March 27-29, 2015.

347 – A. Lemos, P. Brandão, A. Palmeira, M. Pinto, L. Saraiva, E. Sousa. “A hybridization approach to obtain new xanthone derivatives as potential inhibitors of p53:MDM2 interaction”, III Encontro Nacional de Estudantes de Qumíca, Aveiro, Portugal, March 27-29, 2015.P9.

346- – Neves, A.R.; Correia-da-Silva, M.; Sousa, E.; Duarte, P.; Silva, P; Bousbaaa, H.; Pinto, M. Acetylated flavonoids and xanthones: synthesis and screeningfor antitumor activity. III Encontro Nacional de Estudantes de Química, Aveiro, Portugal, March 27-29, 2015.

345 – Sara Gomes, Leão, M., Soares, J., Raimundo, R., Ramos H., Bessa C., Queiroz, G., Domingos, S., Palmeira A., Sousa, E., Pinto, M., Inga, A., Cidade, H., Saraiva, L. A new inhibitor of the p53-MDM2 interaction derived from naturally occurring chalcones. XLV Reunião Anual da Sociedade Portuguesa de Farmacologia, Lisboa, Portugal, 5-6 February2015., S12C78.

344 – Renata Silva, Andreia Palmeira, Helena Carmo, Daniel Barbosa, Mariline Gameiro, Ana Gomes, Ana Mafalda Paiva, Sara Gomes, Emília Sousa, Madalena Pinto, Maria de Lourdes Bastos, Fernando Remião. P-glycoprotein induction and activation by newly synthetized (thio)xanthones: in vitro and in silico studies. XLV Reunião Anual da Sociedade Portuguesa de Farmacologia, Lisboa, Portugal, 5-6 February2015.

343- R. T. Lima, D. Pereira, H. Seca, J. Soares, S. Gomes, L. Raimundo, C. Maciel, M. Pinto, L. Saraiva, H. Cidade, M. H. Vasconcelos, Synthesis, screening and evaluation of the activity of new p53 activators in human tumour cell lines, I3S 4th Annual Meeting IBMC/INEB/IPATIMUP, de Varzim, Portugal, 30-31 October 2014 (Poster nº 60, pg 40)

342 – R. T. Lima, D. Sousa, N. Mendes, R. Matthiesen, A. S. Gomes, M. M. Pinto, E. Sousa,M. H. Vasconcelos, TXA1.HCl induces autophagy in NCI-H460 cells and reduces the growth of these lung cancer cells xenografted in nude mice, I3S 4th Annual Meeting IBMC/INEB/IPATIMUP, de Varzim, Portugal, 30-31 October 2014 (Poster nº 25, pg 35)

341 – Emilia Sousa, Marta Correia-da-Silva, Sara Cravo, Artur Silva, Madalena Pinto, Parallel Microwave-Accelerated Synthesis of a Series of Triazole-Linked Xanthone Glycosides, EFMC, XXIII International Symposium on Medicinal Chemistry, N015, ChemMedChem, 220, Book of Abstracts, EFMC, International Symposium on Medicinal Chemistry, Lisbon, Portugal 7-11 September 2014

340 – José Soares, Diogo Marques, João Neves, Ricardo Vieira, Salette Reis, Madalena Pinto, Carlos Azevedo, Carlos Afonso, Multidimensional Optimization of Potential Antitumor Pyranoxanthones: Synthesis and Pharmacokinetics, EFMC, XXIII International Symposium on Medicinal Chemistry, O019, ChemMedChem, 237-238 WILEY-VCH Verlag GmbH & Co. KGaA, Book of Abstracts Lisbon, Portugal 7-11September 2014

339 – Pedro Brandão, Sylvie Carvalho, Daniela Pereira, Joana Soares, Sara Cravo, Lucília Saraiva, Madalena Pinto, Honorina Cidade, Chalcones as Promising Small-Molecule Inhibitors of p53–MDM2 Interaction, EFMC, XXIII International Symposium on Medicinal Chemistry, Y015, ChemMedChem, 416, Book of Abstracts, EFMC, International Symposium on Medicinal Chemistry, Lisbon, Portugal 7-11September 2014

338 – Kamonporn Masawang, Madalena Pedro, Honorina Cidade, Rita Reis, Hassan Bousbaa and Madalena Pinto, 1,4, 2’,4’-dihydroxy-3,4,5-trimethoxychalcone acts as anti-mitotic agent and induces mitotic catastrophe in MCF-7 breast cancer cells, R065, EFMC, International Symposium on Medicinal Chemistry, Lisbon, Portugal 7-11September 2014

337 – Silva, R., Gameiro, M., Sousa, E., Carmo, H., Paiva, A. M., Palmeira, A., Barbosa, D., Pinto, M., Bastos, M. L., Remião, F., New thioxanthones and dihydroxylated xanthones as P-glycoprotein inducers/activators, EUROTOX 2014, 50th Congress of the European Societies of Toxicology, Edinburgh, Scotland, 7 – 10 September, 2014

366- Paula Cardoso, Marta Correia-da-Silva, Bárbara Duarte, Franklim Marques, Emília Sousa and M. Pinto, Synthesis of a potential orally-active antithrombotic small molecule, 4th Portuguese Young Chemists Meeting, Coimbra, Portugal, April 29-30, May 1, 2014

365- P. Cardoso, M. Correia-da-Silva, E. Sousa and M. Pinto, Alkyne-azide “click” chemistry in designing sugar-based bioactive compounds, IJUP’14 – 7º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 12-14 February 2013, pg. 576

364- R. Vieira, D. Marques, J. Neves, J. Soares, A. Palmeira, S. Reis, M. Pinto, C. Azevedo, C. Afonso, A computational study to investigate the binding of new potential antitumor xanthone derivatives to human serum albumin, IJUP’14 – 7º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 12-14 February 2013, pg. 566

363- J. Neves, D. Marques, R. Vieira, J. Soares, S. Reis, M. Pinto, C. Azevedo, C. Afonso, Potential antitumour xanthones: synthesis and pharmacokinetics, IJUP’14 – 7º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 12-14 February 2013, pg. 565

362- D. Pereira, S. Carvalho, J. Soares, S. Cravo, L. Saraiva, M. Pinto, H. Cidade, New inhibitors of p53-MDM2 interaction with chalcone scaffold, IJUP’14 – 7º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 12-14 February 2013, pg. 559

361 – D. Marques, J. Neves, R. Vieira, J. Soares, S. Reis, M. Pinto, C. Azevedo, C. Afonso, Expanding the chemical space of antitumor xanthones: a new route paved by a chromene moiety, IJUP’14 – 7º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 12-14 February 2013, pg. 558

360 – D. Torres, A. Marques, S. Monteiro, C. Carneiro, A. Santos, C. Fernandes, A. Palmeira, M.H. Vasconcelos, S. Reis and M. Pinto, Chiral xanthones: Synthesis, biological evaluation and molecular docking as inhibitors of P-glycoprotein (Pgp), phospholipase A2 (PLA2) and cicloxygenases (COX-1 and 2), IJUP’14 – 7º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 12-14 February 2013, pg. 431

359- A. Pereira, M. Rezende, S. Cravo, L. Saraiva, M. Pinto, H. Cidade, Synthesis of alkylated flavonoids with potential antitumor activity, 8th YES Meeting 13 – Eighth Young European Scientists Meeting, 19-22 September 2013 Faculty of Medicine, University of Porto, PS65, 135

358  – S.Carvalho,J. Soares, S. Cravo, L. Saraiva, M. Pinto, H. Cidade, Synthesis chalcones with potential activity in the p53-MDM2 interaction, 10ENQO-1SLB, Faculty of Pharmacy, University of Lisbon, Lisbon, Portugal, 04-06 September 2013, PC176, pg 275

357  – D. Pereira, S. Cravo, L. Saraiva, M. Pinto, H. Cidade, Synthesis of 2’,4’-dihydroxy-3,4,5-3’-propylchalcone analogues with potential antitumor activity, 10ENQO-1SLB, Faculty of Pharmacy, University of Lisbon, Lisbon, Portugal, 04-06 September 2013, PC146, pg 245.

356 –M. Correia-da-Silva, M. Patrão, E. Sousa, M. Pinto, Synthesis of polydulfated diosmin conjugates as potential orally-active antithrombotic agents, 10ENQO-1SLB, Faculty of Pharmacy, University of Lisbon, Lisbon, Portugal, 04-06 September 2013, PC121, pg 220.

355 – A. S. Gomes, S. Cravo, E. Sousa, M. Pinto, Microwave-assisted CuI catalysis to improve the synthesis of aminated thioxanthones, 10ENQO-1SLB, Faculty of Pharmacy, University of Lisbon, Lisbon, Portugal, 04-06 September 2013, PC109, pg 208.

354 – A. Pereira, S. Cravo, L. Saraiva, M. Pinto, H. Cidade, Synthesis by MAOS of alkylated derivatives of a bioactive natural flavone, 10ENQO-1SLB, Faculty of Pharmacy, University of Lisbon, Lisbon, Portugal, 04-06 September 2013, PC10, pg 109.

353- Sutsawat Duangsrisai, Madalena Pinto, Anake Kijjoa, Hydroxylated Xanthones from Garcinia succifolia KRUZ, Trends in natural products research: a young scientists meeting of PSE and ÖPhG, University C entre Obergurgl/Tyrol, Austria, 21 – 25 July 2013

352 – A. S. Gomes, T. Oliveira, D. Sousa, R. T. Lima, J. A. R. Salvador, M. H. Vasconcelos, M. M. Pinto, E. Sousa. Studies of the possible oxidative metabolism of a promising antitumor compound. XXII Porto Cancer Meeting & III Porto-Bordeaux Joint Meeting “Translational Research in Cancer – Bringing Basic Science an Pathology to Clinical Oncology”, IPATIMUP, Porto, Portugal, 11-12 April, 2013, P-26, pp 60.

351 – João Filipe Barbosa, Diana Sousa, Raquel T. Lima, Hassan Bousbaa, A. S. Gomes, Madalena M. Pinto, Emília Sousa, M. Helena Vasconcelos and Madalena Pedro, A potent small molecule that irreversible induces cell death in MCF-7 breast cancer cells, XXII Porto Cancer Meeting & III Porto-Bordeaux Joint Meeting “Translational Research in Cancer – Bringing Basic Science an Pathology to Clinical Oncology”, IPATIMUP, Porto, Portugal, 11-12 April, 2013, P-42, pp 76.

350 – Kamonporn Masawang, Madalena Pedro, Honorina Cidade, Hassan Bousbaa, Madalena Pinto, A new small molecule with anti-mitotic activity in mcf-7 breast cancer cells, XXII Porto Cancer Meeting & III Porto-Bordeaux Joint Meeting “Translational Research in Cancer – Bringing Basic Science an Pathology to Clinical Oncology”, IPATIMUP, Porto, Portugal, 11-12 April, 2013, P-44, pp 78.

349 – Raquel T. Lima, Diana Sousa, Kantima Choosang, Pannee Pakkong, Andreia Palmeira, A. M. Paiva, Hugo Seca, Fátima Cerqueir, Madalena Pedro, Madalena M. Pinto, Emília Sousa and M. Helena Vasconcelos, A small molecule which affects the viability of a melanoma cell line through the induction of autophagy, XXII Porto Cancer Meeting & III Porto-Bordeaux Joint Meeting “Translational Research in Cancer – Bringing Basic Science an Pathology to Clinical Oncology”, IPATIMUP, Porto, Portugal, 11-12 April, 2013, P-35.

348- Sara Leirosa, Clara C. S. Sousa, M. J. Sottomayor, Madalena Pinto, Effect of 3,4-dihydroxyxanthone on the stability of DNA, 11º Encontro Nacional de Química-Física,Faculdade de Ciências UP, Porto, Portugal, 9-10 May, 2013

347 – Raquel T. Lima, Diana Sousa, Kantima Choosang, Pannee Pakkong, Andreia Palmeira, A. M. Paiva, Hugo Seca, Fátima Cerqueira, Madalena Pedro, Madalena M. Pinto, Emília Sousa, and M. Helena Vasconcelos, A potente thioxanthone which induces autophagy and cell death in a melanoma cell line, International Congress on Target Anticancer Therapies, Paris, France, 4-6 March, 2013, P-03.18, pp i26.

346 – S. Carvalho, S. Cravo, L. Saraiva, M. Pinto, H. Cidade, Synthesis of prenylchalcones with potential antitumor activity, IJUP’13 – 6º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 13-15 February 2013, pg. 564

345 – A. Pereira, M. Rezende, S. Cravo, L. Saraiva, M. Pinto, H. Cidade Synthesis of alkylated derivatives of a bioactive natural flavone, IJUP’13 – 6º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 13-15 February 2013, pg. 561

344 – C. Sobral, A.M. Paiva, E. Sousa and M. Pinto, Synthesis of 3,4-oxygenated xanthone derivatives, IJUP’13 – 6º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 13-15 February 2013, pg. 560

327 – D. Pereira, S. Cravo, L. Saraiva, M. Pinto, H. Cidade, Synthesis of 2’-hydroxy-3,4,4’,5,6’-pentamethoxy-3’-propylchalcone analogues with potential antitumor activity, IJUP’13 – 6º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 13-15 February 2013, pg. 559

343 – S. Domingues, S. Cravo, M. Pinto, H. Cidade, Synthesis by MAOS of some chalcone derivatives, IJUP’13 – 6º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 13-15 February 2013, pg. 558

342 – A. Marques, D. Torres, S. Monteiro, C. Fernandes, E. Tiritan and M. Pinto, Synthetic strategy to obtain chiral derivatives of xanthones, IJUP’13 – 6º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 13-15 February 2013, pg. 519

341 – M. Patrão, M. Correia-da-Silva, E. Sousa and M. M. M. Pinto, Synthesis of prodrugs of polysulfated diosmin as potential orally-active antithrombotic agents, IJUP’13 – 6º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 13-15 February 2013, pg. 518

340 – D. Marques, R. Vieira, J. Neve , J. X. Soares , C. Azevedo , Carlos M. M. Afonso, M. S. Reis, M. M. Pinto, Multidimensional optimization of xanthones with potential antitumor activity: plasma protein bindingIJUP’13 – 6º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 13-15 February 2013, pg. 440

339 – A. Faria, A. P. Almeida, M. H. Vasconcelos, M. Pinto and A. Kijjoa, Chemical and in vitro studies of growth inhibitory effects on human cancer cell lines of an extract of the marine fungus Neosartorya spinosa, IJUP’13 – 6º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 13-15 February 2013, pg. 367

338 – M.T. Serdeiro, E. Cardoso, D. S. A. Chaves, M. Pinto, A. P. Almeida and M. Maleck, Cecropia catharinensis: a plant with biological properties against Aedes aegypti, IJUP’13 – 6º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 13-15 February 2013, pg. 366

337 – F. Durães, É. Cavalcanti Cardoso, S. Cravo, J. F. Barbosa, M. Pedro, M. Pinto and A. P. de Almeida, Cecropia catarinensis: A plant with antitumor potencial, IJUP’13 – 6º Encontro de Investigação Jovem da Universidade do Porto, Porto, Portugal, 13-15 February 2013, pg. 365